Immunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring
Cosmetics analysis represents a rapidly expanding field of analytical chemistry as new cosmetic formulations are increasingly in demand on the market and the ingredients required for their production are constantly evolving. Each country applies strict legislation regarding substances in the final p...
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MDPI AG
2021
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oai:doaj.org-article:791a5d76e3084c0d9543785b22cf3fa52021-11-25T18:51:13ZImmunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring10.3390/pr91119822227-9717https://doaj.org/article/791a5d76e3084c0d9543785b22cf3fa52021-11-01T00:00:00Zhttps://www.mdpi.com/2227-9717/9/11/1982https://doaj.org/toc/2227-9717Cosmetics analysis represents a rapidly expanding field of analytical chemistry as new cosmetic formulations are increasingly in demand on the market and the ingredients required for their production are constantly evolving. Each country applies strict legislation regarding substances in the final product that must be prohibited or regulated. To verify the compliance of cosmetics with current regulations, official analytical methods are available to reveal and quantitatively determine the analytes of interest. However, since ingredients, and the lists of regulated/prohibited substances, rapidly change, dedicated analytical methods must be developed ad hoc to fulfill the new requirements. Research focuses on finding innovative techniques that allow a rapid, inexpensive, and sensitive detection of the target analytes in cosmetics. Among the different methods proposed, immunological techniques are gaining interest, as they make it possible to carry out low-cost analyses on raw materials and finished products in a relatively short time. Indeed, immunoassays are based on the specific and selective antibody/antigen reaction, and they have been extensively applied for clinical diagnostic, alimentary quality control and environmental security purposes, and even for routine analysis. Since the complexity and variability of the matrices, as well as the great variety of compounds present in cosmetics, are analogous with those from food sources, immunological methods could also be applied successfully in this field. Indeed, this would provide a valid approach for the monitoring of industrial production chains even in developing countries, which are currently the greatest producers of cosmetics and the major exporters of raw materials. This review aims to highlight the immunological techniques proposed for cosmetics analysis, focusing on the detection of prohibited/regulated compounds, bacteria and toxins, and allergenic substances, and the identification of counterfeits.Martina ZangheriMaria Maddalena CalabrettaDonato CalabriaJessica FioriMassimo GuardigliElisa MicheliniSonia MelandriAssimo MarisMara MirasoliLuca EvangelistiMDPI AGarticleimmunoassaycosmeticslateral flow immunoassayELISAallergentoxinsChemical technologyTP1-1185ChemistryQD1-999ENProcesses, Vol 9, Iss 1982, p 1982 (2021) |
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immunoassay cosmetics lateral flow immunoassay ELISA allergen toxins Chemical technology TP1-1185 Chemistry QD1-999 |
spellingShingle |
immunoassay cosmetics lateral flow immunoassay ELISA allergen toxins Chemical technology TP1-1185 Chemistry QD1-999 Martina Zangheri Maria Maddalena Calabretta Donato Calabria Jessica Fiori Massimo Guardigli Elisa Michelini Sonia Melandri Assimo Maris Mara Mirasoli Luca Evangelisti Immunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring |
description |
Cosmetics analysis represents a rapidly expanding field of analytical chemistry as new cosmetic formulations are increasingly in demand on the market and the ingredients required for their production are constantly evolving. Each country applies strict legislation regarding substances in the final product that must be prohibited or regulated. To verify the compliance of cosmetics with current regulations, official analytical methods are available to reveal and quantitatively determine the analytes of interest. However, since ingredients, and the lists of regulated/prohibited substances, rapidly change, dedicated analytical methods must be developed ad hoc to fulfill the new requirements. Research focuses on finding innovative techniques that allow a rapid, inexpensive, and sensitive detection of the target analytes in cosmetics. Among the different methods proposed, immunological techniques are gaining interest, as they make it possible to carry out low-cost analyses on raw materials and finished products in a relatively short time. Indeed, immunoassays are based on the specific and selective antibody/antigen reaction, and they have been extensively applied for clinical diagnostic, alimentary quality control and environmental security purposes, and even for routine analysis. Since the complexity and variability of the matrices, as well as the great variety of compounds present in cosmetics, are analogous with those from food sources, immunological methods could also be applied successfully in this field. Indeed, this would provide a valid approach for the monitoring of industrial production chains even in developing countries, which are currently the greatest producers of cosmetics and the major exporters of raw materials. This review aims to highlight the immunological techniques proposed for cosmetics analysis, focusing on the detection of prohibited/regulated compounds, bacteria and toxins, and allergenic substances, and the identification of counterfeits. |
format |
article |
author |
Martina Zangheri Maria Maddalena Calabretta Donato Calabria Jessica Fiori Massimo Guardigli Elisa Michelini Sonia Melandri Assimo Maris Mara Mirasoli Luca Evangelisti |
author_facet |
Martina Zangheri Maria Maddalena Calabretta Donato Calabria Jessica Fiori Massimo Guardigli Elisa Michelini Sonia Melandri Assimo Maris Mara Mirasoli Luca Evangelisti |
author_sort |
Martina Zangheri |
title |
Immunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring |
title_short |
Immunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring |
title_full |
Immunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring |
title_fullStr |
Immunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring |
title_full_unstemmed |
Immunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring |
title_sort |
immunological analytical techniques for cosmetics quality control and process monitoring |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doaj.org/article/791a5d76e3084c0d9543785b22cf3fa5 |
work_keys_str_mv |
AT martinazangheri immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring AT mariamaddalenacalabretta immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring AT donatocalabria immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring AT jessicafiori immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring AT massimoguardigli immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring AT elisamichelini immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring AT soniamelandri immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring AT assimomaris immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring AT maramirasoli immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring AT lucaevangelisti immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring |
_version_ |
1718410653732962304 |