Immunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring

Cosmetics analysis represents a rapidly expanding field of analytical chemistry as new cosmetic formulations are increasingly in demand on the market and the ingredients required for their production are constantly evolving. Each country applies strict legislation regarding substances in the final p...

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Autores principales: Martina Zangheri, Maria Maddalena Calabretta, Donato Calabria, Jessica Fiori, Massimo Guardigli, Elisa Michelini, Sonia Melandri, Assimo Maris, Mara Mirasoli, Luca Evangelisti
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Publicado: MDPI AG 2021
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spelling oai:doaj.org-article:791a5d76e3084c0d9543785b22cf3fa52021-11-25T18:51:13ZImmunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring10.3390/pr91119822227-9717https://doaj.org/article/791a5d76e3084c0d9543785b22cf3fa52021-11-01T00:00:00Zhttps://www.mdpi.com/2227-9717/9/11/1982https://doaj.org/toc/2227-9717Cosmetics analysis represents a rapidly expanding field of analytical chemistry as new cosmetic formulations are increasingly in demand on the market and the ingredients required for their production are constantly evolving. Each country applies strict legislation regarding substances in the final product that must be prohibited or regulated. To verify the compliance of cosmetics with current regulations, official analytical methods are available to reveal and quantitatively determine the analytes of interest. However, since ingredients, and the lists of regulated/prohibited substances, rapidly change, dedicated analytical methods must be developed ad hoc to fulfill the new requirements. Research focuses on finding innovative techniques that allow a rapid, inexpensive, and sensitive detection of the target analytes in cosmetics. Among the different methods proposed, immunological techniques are gaining interest, as they make it possible to carry out low-cost analyses on raw materials and finished products in a relatively short time. Indeed, immunoassays are based on the specific and selective antibody/antigen reaction, and they have been extensively applied for clinical diagnostic, alimentary quality control and environmental security purposes, and even for routine analysis. Since the complexity and variability of the matrices, as well as the great variety of compounds present in cosmetics, are analogous with those from food sources, immunological methods could also be applied successfully in this field. Indeed, this would provide a valid approach for the monitoring of industrial production chains even in developing countries, which are currently the greatest producers of cosmetics and the major exporters of raw materials. This review aims to highlight the immunological techniques proposed for cosmetics analysis, focusing on the detection of prohibited/regulated compounds, bacteria and toxins, and allergenic substances, and the identification of counterfeits.Martina ZangheriMaria Maddalena CalabrettaDonato CalabriaJessica FioriMassimo GuardigliElisa MicheliniSonia MelandriAssimo MarisMara MirasoliLuca EvangelistiMDPI AGarticleimmunoassaycosmeticslateral flow immunoassayELISAallergentoxinsChemical technologyTP1-1185ChemistryQD1-999ENProcesses, Vol 9, Iss 1982, p 1982 (2021)
institution DOAJ
collection DOAJ
language EN
topic immunoassay
cosmetics
lateral flow immunoassay
ELISA
allergen
toxins
Chemical technology
TP1-1185
Chemistry
QD1-999
spellingShingle immunoassay
cosmetics
lateral flow immunoassay
ELISA
allergen
toxins
Chemical technology
TP1-1185
Chemistry
QD1-999
Martina Zangheri
Maria Maddalena Calabretta
Donato Calabria
Jessica Fiori
Massimo Guardigli
Elisa Michelini
Sonia Melandri
Assimo Maris
Mara Mirasoli
Luca Evangelisti
Immunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring
description Cosmetics analysis represents a rapidly expanding field of analytical chemistry as new cosmetic formulations are increasingly in demand on the market and the ingredients required for their production are constantly evolving. Each country applies strict legislation regarding substances in the final product that must be prohibited or regulated. To verify the compliance of cosmetics with current regulations, official analytical methods are available to reveal and quantitatively determine the analytes of interest. However, since ingredients, and the lists of regulated/prohibited substances, rapidly change, dedicated analytical methods must be developed ad hoc to fulfill the new requirements. Research focuses on finding innovative techniques that allow a rapid, inexpensive, and sensitive detection of the target analytes in cosmetics. Among the different methods proposed, immunological techniques are gaining interest, as they make it possible to carry out low-cost analyses on raw materials and finished products in a relatively short time. Indeed, immunoassays are based on the specific and selective antibody/antigen reaction, and they have been extensively applied for clinical diagnostic, alimentary quality control and environmental security purposes, and even for routine analysis. Since the complexity and variability of the matrices, as well as the great variety of compounds present in cosmetics, are analogous with those from food sources, immunological methods could also be applied successfully in this field. Indeed, this would provide a valid approach for the monitoring of industrial production chains even in developing countries, which are currently the greatest producers of cosmetics and the major exporters of raw materials. This review aims to highlight the immunological techniques proposed for cosmetics analysis, focusing on the detection of prohibited/regulated compounds, bacteria and toxins, and allergenic substances, and the identification of counterfeits.
format article
author Martina Zangheri
Maria Maddalena Calabretta
Donato Calabria
Jessica Fiori
Massimo Guardigli
Elisa Michelini
Sonia Melandri
Assimo Maris
Mara Mirasoli
Luca Evangelisti
author_facet Martina Zangheri
Maria Maddalena Calabretta
Donato Calabria
Jessica Fiori
Massimo Guardigli
Elisa Michelini
Sonia Melandri
Assimo Maris
Mara Mirasoli
Luca Evangelisti
author_sort Martina Zangheri
title Immunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring
title_short Immunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring
title_full Immunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring
title_fullStr Immunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring
title_full_unstemmed Immunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring
title_sort immunological analytical techniques for cosmetics quality control and process monitoring
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/791a5d76e3084c0d9543785b22cf3fa5
work_keys_str_mv AT martinazangheri immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring
AT mariamaddalenacalabretta immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring
AT donatocalabria immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring
AT jessicafiori immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring
AT massimoguardigli immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring
AT elisamichelini immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring
AT soniamelandri immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring
AT assimomaris immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring
AT maramirasoli immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring
AT lucaevangelisti immunologicalanalyticaltechniquesforcosmeticsqualitycontrolandprocessmonitoring
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