Analysis of the parathyroid function in maintenance hemodialysis patients from Changchun, China

Objective: To evaluate the parathyroid function in maintenance hemodialysis patients from 4 hemodialysis centers and to analyze the cause of the dysfunction. Methods: This cross-sectional study included patients with chronic renal disease undergoing maintenance hemodialysis treatment at 4 hemodialys...

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Autores principales:	Juan Du, Songyan Wang, Wangbo Yu, Shuang Li, Jingbo Xu
Formato:	article
Lenguaje:	EN
Publicado:	KeAi Communications Co., Ltd. 2017
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/791b71ab0f1f45bf8376bedc140d39b2
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spelling	oai:doaj.org-article:791b71ab0f1f45bf8376bedc140d39b22021-12-02T15:49:44ZAnalysis of the parathyroid function in maintenance hemodialysis patients from Changchun, China2095-882X10.1016/j.cdtm.2017.07.001https://doaj.org/article/791b71ab0f1f45bf8376bedc140d39b22017-09-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095882X17300245https://doaj.org/toc/2095-882XObjective: To evaluate the parathyroid function in maintenance hemodialysis patients from 4 hemodialysis centers and to analyze the cause of the dysfunction. Methods: This cross-sectional study included patients with chronic renal disease undergoing maintenance hemodialysis treatment at 4 hemodialysis centers in Changchun, China, between March 2014 and August 2015. A total of 337 patients were asked to complete a questionnaire including their name, gender, age, hemodialysis duration, the use of calcium carbonate and vitamin D3 supplements, health education status, hemofiltration frequency, appetite, and education level. Serum intact parathyroid hormone (iPTH), phosphorus, total calcium, blood urea nitrogen (BUN), and creatinine (Cre) levels were obtained from clinical information. Patients with iPTH data were divided into 2 groups: Normal group: the patients with an iPTH levelÂ <Â 100Â pg/ml (28 subjects); Abnormal group: the patients with an iPTH levelÂ >Â 100Â pg/ml (136 subjects). Intergroup differences were analyzed using the t-test. The enumeration data were analyzed by the Ï2 test. Results: The iPTH levels were not monitored for 173 maintenance hemodialysis patients (51.3%) but for 164 patients (48.7%). Of the 164 patients, 28 (17.1%) had a normal serum iPTH level, while the other 136 (82.9%) had an abnormal iPTH level. The maintenance hemodialysis duration and phosphorus levels in the Abnormal group were higher than those in the Normal group (PÂ <Â 0.05). The appetites of patients in the Abnormal group were better than those of patients in the Normal group (PÂ <Â 0.05). Conclusions: A lower proportion of patients on hemodialysis had a normal iPTH level. The phosphorus levels of patients on hemodialysis should be controlled via dietary interventions. Keywords: Maintenance hemodialysis, Intact parathyroid hormone, Serum phosphorusJuan DuSongyan WangWangbo YuShuang LiJingbo XuKeAi Communications Co., Ltd.articleMedicine (General)R5-920ENChronic Diseases and Translational Medicine, Vol 3, Iss 3, Pp 181-185 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Juan Du Songyan Wang Wangbo Yu Shuang Li Jingbo Xu Analysis of the parathyroid function in maintenance hemodialysis patients from Changchun, China
description	Objective: To evaluate the parathyroid function in maintenance hemodialysis patients from 4 hemodialysis centers and to analyze the cause of the dysfunction. Methods: This cross-sectional study included patients with chronic renal disease undergoing maintenance hemodialysis treatment at 4 hemodialysis centers in Changchun, China, between March 2014 and August 2015. A total of 337 patients were asked to complete a questionnaire including their name, gender, age, hemodialysis duration, the use of calcium carbonate and vitamin D3 supplements, health education status, hemofiltration frequency, appetite, and education level. Serum intact parathyroid hormone (iPTH), phosphorus, total calcium, blood urea nitrogen (BUN), and creatinine (Cre) levels were obtained from clinical information. Patients with iPTH data were divided into 2 groups: Normal group: the patients with an iPTH levelÂ <Â 100Â pg/ml (28 subjects); Abnormal group: the patients with an iPTH levelÂ >Â 100Â pg/ml (136 subjects). Intergroup differences were analyzed using the t-test. The enumeration data were analyzed by the Ï2 test. Results: The iPTH levels were not monitored for 173 maintenance hemodialysis patients (51.3%) but for 164 patients (48.7%). Of the 164 patients, 28 (17.1%) had a normal serum iPTH level, while the other 136 (82.9%) had an abnormal iPTH level. The maintenance hemodialysis duration and phosphorus levels in the Abnormal group were higher than those in the Normal group (PÂ <Â 0.05). The appetites of patients in the Abnormal group were better than those of patients in the Normal group (PÂ <Â 0.05). Conclusions: A lower proportion of patients on hemodialysis had a normal iPTH level. The phosphorus levels of patients on hemodialysis should be controlled via dietary interventions. Keywords: Maintenance hemodialysis, Intact parathyroid hormone, Serum phosphorus
format	article
author	Juan Du Songyan Wang Wangbo Yu Shuang Li Jingbo Xu
author_facet	Juan Du Songyan Wang Wangbo Yu Shuang Li Jingbo Xu
author_sort	Juan Du
title	Analysis of the parathyroid function in maintenance hemodialysis patients from Changchun, China
title_short	Analysis of the parathyroid function in maintenance hemodialysis patients from Changchun, China
title_full	Analysis of the parathyroid function in maintenance hemodialysis patients from Changchun, China
title_fullStr	Analysis of the parathyroid function in maintenance hemodialysis patients from Changchun, China
title_full_unstemmed	Analysis of the parathyroid function in maintenance hemodialysis patients from Changchun, China
title_sort	analysis of the parathyroid function in maintenance hemodialysis patients from changchun, china
publisher	KeAi Communications Co., Ltd.
publishDate	2017
url	https://doaj.org/article/791b71ab0f1f45bf8376bedc140d39b2
work_keys_str_mv	AT juandu analysisoftheparathyroidfunctioninmaintenancehemodialysispatientsfromchangchunchina AT songyanwang analysisoftheparathyroidfunctioninmaintenancehemodialysispatientsfromchangchunchina AT wangboyu analysisoftheparathyroidfunctioninmaintenancehemodialysispatientsfromchangchunchina AT shuangli analysisoftheparathyroidfunctioninmaintenancehemodialysispatientsfromchangchunchina AT jingboxu analysisoftheparathyroidfunctioninmaintenancehemodialysispatientsfromchangchunchina
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Analysis of the parathyroid function in maintenance hemodialysis patients from Changchun, China

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