Middle-aged individuals may be in a perpetual state of H3N2 influenza virus susceptibility

Influenza exposure in early childhood can affect the immune response to distinct viral strains later in life. Here, Gouma et al. show that contemporary 3c2.A H3N2 virus infections boost non-neutralizing H3N2 antibodies in middle-aged individuals, potentially leaving them vulnerable to recurrent infe...

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Autores principales:	Sigrid Gouma, Kangchon Kim, Madison E. Weirick, Megan E. Gumina, Angela Branche, David J. Topham, Emily T. Martin, Arnold S. Monto, Sarah Cobey, Scott E. Hensley
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/792227af26bb4898b50fc41e24abb5db
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spelling	oai:doaj.org-article:792227af26bb4898b50fc41e24abb5db2021-12-02T14:55:09ZMiddle-aged individuals may be in a perpetual state of H3N2 influenza virus susceptibility10.1038/s41467-020-18465-x2041-1723https://doaj.org/article/792227af26bb4898b50fc41e24abb5db2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18465-xhttps://doaj.org/toc/2041-1723Influenza exposure in early childhood can affect the immune response to distinct viral strains later in life. Here, Gouma et al. show that contemporary 3c2.A H3N2 virus infections boost non-neutralizing H3N2 antibodies in middle-aged individuals, potentially leaving them vulnerable to recurrent infections.Sigrid GoumaKangchon KimMadison E. WeirickMegan E. GuminaAngela BrancheDavid J. TophamEmily T. MartinArnold S. MontoSarah CobeyScott E. HensleyNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sigrid Gouma Kangchon Kim Madison E. Weirick Megan E. Gumina Angela Branche David J. Topham Emily T. Martin Arnold S. Monto Sarah Cobey Scott E. Hensley Middle-aged individuals may be in a perpetual state of H3N2 influenza virus susceptibility
description	Influenza exposure in early childhood can affect the immune response to distinct viral strains later in life. Here, Gouma et al. show that contemporary 3c2.A H3N2 virus infections boost non-neutralizing H3N2 antibodies in middle-aged individuals, potentially leaving them vulnerable to recurrent infections.
format	article
author	Sigrid Gouma Kangchon Kim Madison E. Weirick Megan E. Gumina Angela Branche David J. Topham Emily T. Martin Arnold S. Monto Sarah Cobey Scott E. Hensley
author_facet	Sigrid Gouma Kangchon Kim Madison E. Weirick Megan E. Gumina Angela Branche David J. Topham Emily T. Martin Arnold S. Monto Sarah Cobey Scott E. Hensley
author_sort	Sigrid Gouma
title	Middle-aged individuals may be in a perpetual state of H3N2 influenza virus susceptibility
title_short	Middle-aged individuals may be in a perpetual state of H3N2 influenza virus susceptibility
title_full	Middle-aged individuals may be in a perpetual state of H3N2 influenza virus susceptibility
title_fullStr	Middle-aged individuals may be in a perpetual state of H3N2 influenza virus susceptibility
title_full_unstemmed	Middle-aged individuals may be in a perpetual state of H3N2 influenza virus susceptibility
title_sort	middle-aged individuals may be in a perpetual state of h3n2 influenza virus susceptibility
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/792227af26bb4898b50fc41e24abb5db
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Middle-aged individuals may be in a perpetual state of H3N2 influenza virus susceptibility

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