Use of Computer Models and Animations to Teach about B Cell (antibody) and T Cell Recombination (TCR)

This manuscript presents a technique on how to use both computer models and animations to teach about the process of recombination. This is a traditionally difficult topic taught in both microbiology and immunology classes. Active learning techniques are presented to help teach the students about th...

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Autores principales: Fran Norflus, Neil Charles Allen
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
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Acceso en línea:https://doaj.org/article/7923f576cf5b4b57bb80245f8ac72e2f
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spelling oai:doaj.org-article:7923f576cf5b4b57bb80245f8ac72e2f2021-11-15T15:03:46ZUse of Computer Models and Animations to Teach about B Cell (antibody) and T Cell Recombination (TCR)10.1128/jmbe.v17i2.10791935-78851935-7877https://doaj.org/article/7923f576cf5b4b57bb80245f8ac72e2f2016-05-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/jmbe.v17i2.1079https://doaj.org/toc/1935-7877https://doaj.org/toc/1935-7885This manuscript presents a technique on how to use both computer models and animations to teach about the process of recombination. This is a traditionally difficult topic taught in both microbiology and immunology classes. Active learning techniques are presented to help teach the students about this process. In more introductory classes, the instructor can teach the students about how antibody molecules are made. In more advanced classes, this topic can be expanded and the students can also learn how T cell receptors are made. Initially, the students are shown an animation of antibody recombination where they can select to see the different segments coming together which are randomly generated. Then, they look at their computers to see the different segments of antibodies shown in different colors and they can select one fragment from the different sections. We feel that the use of these different techniques is important in reinforcing the topic.Fran NorflusNeil Charles AllenAmerican Society for MicrobiologyarticleSpecial aspects of educationLC8-6691Biology (General)QH301-705.5ENJournal of Microbiology & Biology Education, Vol 17, Iss 2, Pp 292-293 (2016)
institution DOAJ
collection DOAJ
language EN
topic Special aspects of education
LC8-6691
Biology (General)
QH301-705.5
spellingShingle Special aspects of education
LC8-6691
Biology (General)
QH301-705.5
Fran Norflus
Neil Charles Allen
Use of Computer Models and Animations to Teach about B Cell (antibody) and T Cell Recombination (TCR)
description This manuscript presents a technique on how to use both computer models and animations to teach about the process of recombination. This is a traditionally difficult topic taught in both microbiology and immunology classes. Active learning techniques are presented to help teach the students about this process. In more introductory classes, the instructor can teach the students about how antibody molecules are made. In more advanced classes, this topic can be expanded and the students can also learn how T cell receptors are made. Initially, the students are shown an animation of antibody recombination where they can select to see the different segments coming together which are randomly generated. Then, they look at their computers to see the different segments of antibodies shown in different colors and they can select one fragment from the different sections. We feel that the use of these different techniques is important in reinforcing the topic.
format article
author Fran Norflus
Neil Charles Allen
author_facet Fran Norflus
Neil Charles Allen
author_sort Fran Norflus
title Use of Computer Models and Animations to Teach about B Cell (antibody) and T Cell Recombination (TCR)
title_short Use of Computer Models and Animations to Teach about B Cell (antibody) and T Cell Recombination (TCR)
title_full Use of Computer Models and Animations to Teach about B Cell (antibody) and T Cell Recombination (TCR)
title_fullStr Use of Computer Models and Animations to Teach about B Cell (antibody) and T Cell Recombination (TCR)
title_full_unstemmed Use of Computer Models and Animations to Teach about B Cell (antibody) and T Cell Recombination (TCR)
title_sort use of computer models and animations to teach about b cell (antibody) and t cell recombination (tcr)
publisher American Society for Microbiology
publishDate 2016
url https://doaj.org/article/7923f576cf5b4b57bb80245f8ac72e2f
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