Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix

Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix

Colorectal cancers (CRCs) often develop into untreatable metastatic disease of the liver. Here the authors report the modification of extracellular matrix proteins by citrullination in CRC metastases to the liver and propose that inhibition of citrullination could serve as therapeutic avenue in the...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: A. E. Yuzhalin, A. N. Gordon-Weeks, M. L. Tognoli, K. Jones, B. Markelc, R. Konietzny, R. Fischer, A. Muth, E. O’Neill, P. R. Thompson, P. J. Venables, B. M. Kessler, S. Y. Lim, R. J. Muschel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/792ceadda95d4235966746de3a3f6359
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares