Global analysis of glycoproteins identifies markers of endotoxin tolerant monocytes and GPR84 as a modulator of TNFα expression

Global analysis of glycoproteins identifies markers of endotoxin tolerant monocytes and GPR84 as a modulator of TNFα expression

Abstract Exposure of human monocytes to lipopolysaccharide (LPS) induces a temporary insensitivity to subsequent LPS challenges, a cellular state called endotoxin tolerance. In this study, we investigated the LPS-induced global glycoprotein expression changes of tolerant human monocytes and THP-1 ce...

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Autores principales: Mario M. Müller, Roland Lehmann, Tilman E. Klassert, Stella Reifenstein, Theresia Conrad, Christoph Moore, Anna Kuhn, Andrea Behnert, Reinhard Guthke, Dominik Driesch, Hortense Slevogt
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/7933dd5b970a4a05a24a95607778d7de
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