Single-cell transcriptomic analysis reveals disparate effector differentiation pathways in human Treg compartment

Single-cell transcriptomic analysis reveals disparate effector differentiation pathways in human Treg compartment

Human Treg cells are central to immune tolerance, yet their heterogeneity and differentiation remain incompletely understood. Here the authors perform single-cell RNA and T cell receptor sequencing to resolve Treg cells from healthy individuals and patients with or without acute graft-versus-host di...

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Autores principales: Yuechen Luo, Changlu Xu, Bing Wang, Qing Niu, Xiuhua Su, Yingnan Bai, Shuxian Zhu, Chunxiao Zhao, Yunyan Sun, Jiali Wang, Maolan Liu, Xiaolei Sun, Ge Song, Haidong Cui, Xiaoli Chen, Huifang Huang, Haikun Wang, Mingzhe Han, Erlie Jiang, Lihong Shi, Xiaoming Feng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/7942edb4231e4783bfa50aec2783e956
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