LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields
LTP and LTD are involved in shaping hippocampal place field representations. Here, the authors show that de novo pathway-specific hippocampal LTD changes dynamics and stability of newly formed place fields, regulating acquisition and maintenance of novel spatial information in adult rats.
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Nature Portfolio
2021
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oai:doaj.org-article:7955892d980e42c28d73f7ce2fa366092021-12-02T15:08:00ZLTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields10.1038/s41467-020-20317-72041-1723https://doaj.org/article/7955892d980e42c28d73f7ce2fa366092021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20317-7https://doaj.org/toc/2041-1723LTP and LTD are involved in shaping hippocampal place field representations. Here, the authors show that de novo pathway-specific hippocampal LTD changes dynamics and stability of newly formed place fields, regulating acquisition and maintenance of novel spatial information in adult rats.Donovan M. AshbyStan B. FlorescoAnthony G. PhillipsAlexander McGirrJeremy K. SeamansYu Tian WangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021) |
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Science Q Donovan M. Ashby Stan B. Floresco Anthony G. Phillips Alexander McGirr Jeremy K. Seamans Yu Tian Wang LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields |
description |
LTP and LTD are involved in shaping hippocampal place field representations. Here, the authors show that de novo pathway-specific hippocampal LTD changes dynamics and stability of newly formed place fields, regulating acquisition and maintenance of novel spatial information in adult rats. |
format |
article |
author |
Donovan M. Ashby Stan B. Floresco Anthony G. Phillips Alexander McGirr Jeremy K. Seamans Yu Tian Wang |
author_facet |
Donovan M. Ashby Stan B. Floresco Anthony G. Phillips Alexander McGirr Jeremy K. Seamans Yu Tian Wang |
author_sort |
Donovan M. Ashby |
title |
LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields |
title_short |
LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields |
title_full |
LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields |
title_fullStr |
LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields |
title_full_unstemmed |
LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields |
title_sort |
ltd is involved in the formation and maintenance of rat hippocampal ca1 place-cell fields |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/7955892d980e42c28d73f7ce2fa36609 |
work_keys_str_mv |
AT donovanmashby ltdisinvolvedintheformationandmaintenanceofrathippocampalca1placecellfields AT stanbfloresco ltdisinvolvedintheformationandmaintenanceofrathippocampalca1placecellfields AT anthonygphillips ltdisinvolvedintheformationandmaintenanceofrathippocampalca1placecellfields AT alexandermcgirr ltdisinvolvedintheformationandmaintenanceofrathippocampalca1placecellfields AT jeremykseamans ltdisinvolvedintheformationandmaintenanceofrathippocampalca1placecellfields AT yutianwang ltdisinvolvedintheformationandmaintenanceofrathippocampalca1placecellfields |
_version_ |
1718388324286070784 |