LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields

LTP and LTD are involved in shaping hippocampal place field representations. Here, the authors show that de novo pathway-specific hippocampal LTD changes dynamics and stability of newly formed place fields, regulating acquisition and maintenance of novel spatial information in adult rats.

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Auteurs principaux:	Donovan M. Ashby, Stan B. Floresco, Anthony G. Phillips, Alexander McGirr, Jeremy K. Seamans, Yu Tian Wang
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/7955892d980e42c28d73f7ce2fa36609
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id	oai:doaj.org-article:7955892d980e42c28d73f7ce2fa36609
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spelling	oai:doaj.org-article:7955892d980e42c28d73f7ce2fa366092021-12-02T15:08:00ZLTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields10.1038/s41467-020-20317-72041-1723https://doaj.org/article/7955892d980e42c28d73f7ce2fa366092021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20317-7https://doaj.org/toc/2041-1723LTP and LTD are involved in shaping hippocampal place field representations. Here, the authors show that de novo pathway-specific hippocampal LTD changes dynamics and stability of newly formed place fields, regulating acquisition and maintenance of novel spatial information in adult rats.Donovan M. AshbyStan B. FlorescoAnthony G. PhillipsAlexander McGirrJeremy K. SeamansYu Tian WangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Donovan M. Ashby Stan B. Floresco Anthony G. Phillips Alexander McGirr Jeremy K. Seamans Yu Tian Wang LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields
description	LTP and LTD are involved in shaping hippocampal place field representations. Here, the authors show that de novo pathway-specific hippocampal LTD changes dynamics and stability of newly formed place fields, regulating acquisition and maintenance of novel spatial information in adult rats.
format	article
author	Donovan M. Ashby Stan B. Floresco Anthony G. Phillips Alexander McGirr Jeremy K. Seamans Yu Tian Wang
author_facet	Donovan M. Ashby Stan B. Floresco Anthony G. Phillips Alexander McGirr Jeremy K. Seamans Yu Tian Wang
author_sort	Donovan M. Ashby
title	LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields
title_short	LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields
title_full	LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields
title_fullStr	LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields
title_full_unstemmed	LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields
title_sort	ltd is involved in the formation and maintenance of rat hippocampal ca1 place-cell fields
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/7955892d980e42c28d73f7ce2fa36609
work_keys_str_mv	AT donovanmashby ltdisinvolvedintheformationandmaintenanceofrathippocampalca1placecellfields AT stanbfloresco ltdisinvolvedintheformationandmaintenanceofrathippocampalca1placecellfields AT anthonygphillips ltdisinvolvedintheformationandmaintenanceofrathippocampalca1placecellfields AT alexandermcgirr ltdisinvolvedintheformationandmaintenanceofrathippocampalca1placecellfields AT jeremykseamans ltdisinvolvedintheformationandmaintenanceofrathippocampalca1placecellfields AT yutianwang ltdisinvolvedintheformationandmaintenanceofrathippocampalca1placecellfields
_version_	1718388324286070784

LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields

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