LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields

LTP and LTD are involved in shaping hippocampal place field representations. Here, the authors show that de novo pathway-specific hippocampal LTD changes dynamics and stability of newly formed place fields, regulating acquisition and maintenance of novel spatial information in adult rats.

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Autores principales: Donovan M. Ashby, Stan B. Floresco, Anthony G. Phillips, Alexander McGirr, Jeremy K. Seamans, Yu Tian Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7955892d980e42c28d73f7ce2fa36609
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spelling oai:doaj.org-article:7955892d980e42c28d73f7ce2fa366092021-12-02T15:08:00ZLTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields10.1038/s41467-020-20317-72041-1723https://doaj.org/article/7955892d980e42c28d73f7ce2fa366092021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20317-7https://doaj.org/toc/2041-1723LTP and LTD are involved in shaping hippocampal place field representations. Here, the authors show that de novo pathway-specific hippocampal LTD changes dynamics and stability of newly formed place fields, regulating acquisition and maintenance of novel spatial information in adult rats.Donovan M. AshbyStan B. FlorescoAnthony G. PhillipsAlexander McGirrJeremy K. SeamansYu Tian WangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Donovan M. Ashby
Stan B. Floresco
Anthony G. Phillips
Alexander McGirr
Jeremy K. Seamans
Yu Tian Wang
LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields
description LTP and LTD are involved in shaping hippocampal place field representations. Here, the authors show that de novo pathway-specific hippocampal LTD changes dynamics and stability of newly formed place fields, regulating acquisition and maintenance of novel spatial information in adult rats.
format article
author Donovan M. Ashby
Stan B. Floresco
Anthony G. Phillips
Alexander McGirr
Jeremy K. Seamans
Yu Tian Wang
author_facet Donovan M. Ashby
Stan B. Floresco
Anthony G. Phillips
Alexander McGirr
Jeremy K. Seamans
Yu Tian Wang
author_sort Donovan M. Ashby
title LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields
title_short LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields
title_full LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields
title_fullStr LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields
title_full_unstemmed LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields
title_sort ltd is involved in the formation and maintenance of rat hippocampal ca1 place-cell fields
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/7955892d980e42c28d73f7ce2fa36609
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AT alexandermcgirr ltdisinvolvedintheformationandmaintenanceofrathippocampalca1placecellfields
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