L-arginine as a novel target for clinical intervention in inflammatory bowel disease

Arginase-1 (Arg1) and the inducible nitric oxide synthase 2 (NOS2) compete for the common substrate L-arginine, semi-essential amino acid, and central intestinal metabolite. Both enzymes exhibit various, sometimes opposing effects on immune responses, tissue regeneration, or microbial growth and rep...

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Bibliographic Details
Main Authors: Björn Nüse, Jochen Mattner
Format: article
Language:EN
Published: Open Exploration Publishing Inc. 2021
Subjects:
Online Access:https://doaj.org/article/795628a54bfe46eca020af5f2c59efd8
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