CORRELATION BETWEEN SERUM ASCITES ALBUMIN GRADIENT (SAAG) AND ESOPHAGEAL VARICES IN PATIENTS HAVING CHRONIC LIVER DISEASE

Objective: To determine the correlation between level of serum-ascites albumin gradient (SAAG) grading of esophageal varices (EV), in patients having chronic liver disease. Study Design: Prospective, observational and a cross sectional study. Place and Duration of Study: Medical Unit III, Sand...

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Autores principales: Nabeela Iqbal, Syed Khalid Shah, Shamima Hanif
Formato: article
Lenguaje:EN
Publicado: Army Medical College Rawalpindi 2019
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Acceso en línea:https://doaj.org/article/7957f5beed394692beade765d9cb4589
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Sumario:Objective: To determine the correlation between level of serum-ascites albumin gradient (SAAG) grading of esophageal varices (EV), in patients having chronic liver disease. Study Design: Prospective, observational and a cross sectional study. Place and Duration of Study: Medical Unit III, Sandeman Provincial Hospital Quetta, form Oct 2015 to Apr 2016. Material and Methods: Patients with diagnosis of cirrhosis were enrolled. Detailed history, physical examination and biochemical measurements were recorded. Patients underwent upper GI endoscopy for grading of esophageal varices. Results: Eighty patients fulfilling the inclusion criteria were included in this study. There were 56 (70%) males and 24 (30%) females. The mean ± standard deviation age of study population was 44.86 ± 12.319 years. On analysis of age group it was observed that 40 (50%) patients were less than 40 years of age, 73 (91.25%) patients had SAAG value above 1.1 mg/dl. On analysis of correlation of SAAG with the grade of varices, a strong association was observed (r=0.631). Conclusion: An association, in the patients having ascites, between the level of SAAG and the development of esophageal varices is present. Patients having a high SAAG were found with more commonly present Esophageal varices thus establishing a high probability of finding EV in patients with higher values SAAG.