Creb5 establishes the competence for Prg4 expression in articular cartilage

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Creb5 establishes the competence for Prg4 expression in articular cartilage

Zhang et al. identify Creb5 as a transcription factor that is required for induction of Prg4 expression by TGFβ and EGFR ligands. They show that Creb5 directly binds to two Prg4 promoter-proximal regulatory elements, working together with a more distal regulatory element to drive induction of Prg4 b...

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Detalles Bibliográficos
Autores principales:	Cheng-Hai Zhang, Yao Gao, Unmesh Jadhav, Han-Hwa Hung, Kristina M. Holton, Alan J. Grodzinsky, Ramesh A. Shivdasani, Andrew B. Lassar
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/7960c992d8174a428cf9f533ac859690
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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