Novel biomarkers for prediabetes, diabetes, and associated complications

Brenda Dorcely,1 Karin Katz,1 Ram Jagannathan,2 Stephanie S Chiang,1 Babajide Oluwadare,1 Ira J Goldberg,1 Michael Bergman1 1New York University School of Medicine, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, NYU Langone Medical Center, New York, NY, 2Department of Gl...

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Autores principales:	Dorcely B, Katz K, Jagannathan R, Chiang SS, Oluwadare B, Goldberg IJ, Bergman M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	Prediabetes Biomarkers Inflammatory Markers Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/796881bf265d431a9632d4c214624ac8
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spelling	oai:doaj.org-article:796881bf265d431a9632d4c214624ac82021-12-02T00:23:40ZNovel biomarkers for prediabetes, diabetes, and associated complications1178-7007https://doaj.org/article/796881bf265d431a9632d4c214624ac82017-08-01T00:00:00Zhttps://www.dovepress.com/novel-biomarkers-for-prediabetes-diabetes-and-associated-complications-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Brenda Dorcely,1 Karin Katz,1 Ram Jagannathan,2 Stephanie S Chiang,1 Babajide Oluwadare,1 Ira J Goldberg,1 Michael Bergman1 1New York University School of Medicine, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, NYU Langone Medical Center, New York, NY, 2Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA Abstract: The number of individuals with prediabetes is expected to grow substantially and estimated to globally affect 482 million people by 2040. Therefore, effective methods for diagnosing prediabetes will be required to reduce the risk of progressing to diabetes and its complications. The current biomarkers, glycated hemoglobin (HbA1c), fructosamine, and glycated albumin have limitations including moderate sensitivity and specificity and are inaccurate in certain clinical conditions. Therefore, identification of additional biomarkers is being explored recognizing that any single biomarker will also likely have inherent limitations. Therefore, combining several biomarkers may more precisely identify those at high risk for developing prediabetes and subsequent progression to diabetes. This review describes recently identified biomarkers and their potential utility for addressing the burgeoning epidemic of dysglycemic disorders. Keywords: prediabetes, biomarkers, inflammatory markers, diabetes, diabetes complicationsDorcely BKatz KJagannathan RChiang SSOluwadare BGoldberg IJBergman MDove Medical PressarticlePrediabetesBiomarkersInflammatory MarkersSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 10, Pp 345-361 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Prediabetes Biomarkers Inflammatory Markers Specialties of internal medicine RC581-951
spellingShingle	Prediabetes Biomarkers Inflammatory Markers Specialties of internal medicine RC581-951 Dorcely B Katz K Jagannathan R Chiang SS Oluwadare B Goldberg IJ Bergman M Novel biomarkers for prediabetes, diabetes, and associated complications
description	Brenda Dorcely,1 Karin Katz,1 Ram Jagannathan,2 Stephanie S Chiang,1 Babajide Oluwadare,1 Ira J Goldberg,1 Michael Bergman1 1New York University School of Medicine, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, NYU Langone Medical Center, New York, NY, 2Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA Abstract: The number of individuals with prediabetes is expected to grow substantially and estimated to globally affect 482 million people by 2040. Therefore, effective methods for diagnosing prediabetes will be required to reduce the risk of progressing to diabetes and its complications. The current biomarkers, glycated hemoglobin (HbA1c), fructosamine, and glycated albumin have limitations including moderate sensitivity and specificity and are inaccurate in certain clinical conditions. Therefore, identification of additional biomarkers is being explored recognizing that any single biomarker will also likely have inherent limitations. Therefore, combining several biomarkers may more precisely identify those at high risk for developing prediabetes and subsequent progression to diabetes. This review describes recently identified biomarkers and their potential utility for addressing the burgeoning epidemic of dysglycemic disorders. Keywords: prediabetes, biomarkers, inflammatory markers, diabetes, diabetes complications
format	article
author	Dorcely B Katz K Jagannathan R Chiang SS Oluwadare B Goldberg IJ Bergman M
author_facet	Dorcely B Katz K Jagannathan R Chiang SS Oluwadare B Goldberg IJ Bergman M
author_sort	Dorcely B
title	Novel biomarkers for prediabetes, diabetes, and associated complications
title_short	Novel biomarkers for prediabetes, diabetes, and associated complications
title_full	Novel biomarkers for prediabetes, diabetes, and associated complications
title_fullStr	Novel biomarkers for prediabetes, diabetes, and associated complications
title_full_unstemmed	Novel biomarkers for prediabetes, diabetes, and associated complications
title_sort	novel biomarkers for prediabetes, diabetes, and associated complications
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/796881bf265d431a9632d4c214624ac8
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Novel biomarkers for prediabetes, diabetes, and associated complications

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