Acral lentiginous melanoma in the Turkish population and a new dermoscopic clue for the diagnosis

Background: The incidence of acral lentiginous melanoma (ALM) in Caucasians is low. Dermoscopy enhances diagnosis of ALM; however, diagnostic accuracy may sometimes be poor due to the considerable proportion of amelanotic ALM variants. Objectives: To calculate the proportion of ALM among all mel...

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Autores principales:	Fezal Ozdemir, Micol A. Errico, Banu Yaman, Isil Karaarslan
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2018
Materias:	acral lentiginous melanoma amelanotic melanoma nail unit melanoma parallel-ridge pattern dermoscopy Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/796a128b811443a29a5f9e50b668055a
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spelling	oai:doaj.org-article:796a128b811443a29a5f9e50b668055a2021-11-17T08:30:18ZAcral lentiginous melanoma in the Turkish population and a new dermoscopic clue for the diagnosis2160-9381https://doaj.org/article/796a128b811443a29a5f9e50b668055a2018-04-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/371https://doaj.org/toc/2160-9381 Background: The incidence of acral lentiginous melanoma (ALM) in Caucasians is low. Dermoscopy enhances diagnosis of ALM; however, diagnostic accuracy may sometimes be poor due to the considerable proportion of amelanotic ALM variants. Objectives: To calculate the proportion of ALM among all melanoma subtypes and to determine the frequency of dermoscopic features of ALM in the Turkish population. Methods: Out of 612 melanomas, there were 70 cases of ALM, of which 46 showed sufficient image quality for retrospective study of dermoscopic features. Data from patients and their lesions was classified according to clinical features and histopathologic parameters. The dermoscopic variables evaluated were based on pertinent literature on dermoscopy of acral melanocytic neoplasms. Results: The prevalence of ALM among all melanoma subtypes was 11.4%. Parallel-ridge pattern (PRP) was detected in 60.8% of cases and irregular diffuse pigmentation (IDP) in 28.3%. The ALMs were amelanotic in 24%, showing an atypical vascular pattern in all cases; a new dermoscopic pattern, named “vascularized parallel-ridge pattern” (VPRP), was detected in 13% of ALMs. Irregular lines were observed in 81.8% of subungual melanomas and were often associated with a multicolored background. Conclusions: ALM has site-specific dermoscopic patterns, with PRP being the most prevalent pattern. The newly described VPRP pattern may be an additional clue for ALM diagnosis, especially in thin amelanotic melanomas. Fezal OzdemirMicol A. ErricoBanu YamanIsil KaraarslanMattioli1885articleacral lentiginous melanomaamelanotic melanomanail unit melanomaparallel-ridge patterndermoscopyDermatologyRL1-803ENDermatology Practical & Conceptual, Vol 8, Iss 1 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	acral lentiginous melanoma amelanotic melanoma nail unit melanoma parallel-ridge pattern dermoscopy Dermatology RL1-803
spellingShingle	acral lentiginous melanoma amelanotic melanoma nail unit melanoma parallel-ridge pattern dermoscopy Dermatology RL1-803 Fezal Ozdemir Micol A. Errico Banu Yaman Isil Karaarslan Acral lentiginous melanoma in the Turkish population and a new dermoscopic clue for the diagnosis
description	Background: The incidence of acral lentiginous melanoma (ALM) in Caucasians is low. Dermoscopy enhances diagnosis of ALM; however, diagnostic accuracy may sometimes be poor due to the considerable proportion of amelanotic ALM variants. Objectives: To calculate the proportion of ALM among all melanoma subtypes and to determine the frequency of dermoscopic features of ALM in the Turkish population. Methods: Out of 612 melanomas, there were 70 cases of ALM, of which 46 showed sufficient image quality for retrospective study of dermoscopic features. Data from patients and their lesions was classified according to clinical features and histopathologic parameters. The dermoscopic variables evaluated were based on pertinent literature on dermoscopy of acral melanocytic neoplasms. Results: The prevalence of ALM among all melanoma subtypes was 11.4%. Parallel-ridge pattern (PRP) was detected in 60.8% of cases and irregular diffuse pigmentation (IDP) in 28.3%. The ALMs were amelanotic in 24%, showing an atypical vascular pattern in all cases; a new dermoscopic pattern, named “vascularized parallel-ridge pattern” (VPRP), was detected in 13% of ALMs. Irregular lines were observed in 81.8% of subungual melanomas and were often associated with a multicolored background. Conclusions: ALM has site-specific dermoscopic patterns, with PRP being the most prevalent pattern. The newly described VPRP pattern may be an additional clue for ALM diagnosis, especially in thin amelanotic melanomas.
format	article
author	Fezal Ozdemir Micol A. Errico Banu Yaman Isil Karaarslan
author_facet	Fezal Ozdemir Micol A. Errico Banu Yaman Isil Karaarslan
author_sort	Fezal Ozdemir
title	Acral lentiginous melanoma in the Turkish population and a new dermoscopic clue for the diagnosis
title_short	Acral lentiginous melanoma in the Turkish population and a new dermoscopic clue for the diagnosis
title_full	Acral lentiginous melanoma in the Turkish population and a new dermoscopic clue for the diagnosis
title_fullStr	Acral lentiginous melanoma in the Turkish population and a new dermoscopic clue for the diagnosis
title_full_unstemmed	Acral lentiginous melanoma in the Turkish population and a new dermoscopic clue for the diagnosis
title_sort	acral lentiginous melanoma in the turkish population and a new dermoscopic clue for the diagnosis
publisher	Mattioli1885
publishDate	2018
url	https://doaj.org/article/796a128b811443a29a5f9e50b668055a
work_keys_str_mv	AT fezalozdemir acrallentiginousmelanomaintheturkishpopulationandanewdermoscopicclueforthediagnosis AT micolaerrico acrallentiginousmelanomaintheturkishpopulationandanewdermoscopicclueforthediagnosis AT banuyaman acrallentiginousmelanomaintheturkishpopulationandanewdermoscopicclueforthediagnosis AT isilkaraarslan acrallentiginousmelanomaintheturkishpopulationandanewdermoscopicclueforthediagnosis
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Acral lentiginous melanoma in the Turkish population and a new dermoscopic clue for the diagnosis

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