Trabecular and cortical mandibular bone investigation in familial adenomatous polyposis patients

Abstract Mandibular cortical and trabecular bone abnormalities in patients with familial adenomatous polyposis (FAP) were evaluated using dental panoramic radiographs (DPR) radiomorphometric indices and fractal dimension (FD). Sixty DPRs from 15 FAP patients and 45 healthy controls were evaluated. F...

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Autores principales:	Camila Pacheco-Pereira, Yuri Silvestre-Barbosa, Fabiana T. Almeida, Hassem Geha, Andre F. Leite, Eliete N. S. Guerra
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/796ad0343dfc479f80b50dc1f26e8130
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spelling	oai:doaj.org-article:796ad0343dfc479f80b50dc1f26e81302021-12-02T16:55:34ZTrabecular and cortical mandibular bone investigation in familial adenomatous polyposis patients10.1038/s41598-021-88513-z2045-2322https://doaj.org/article/796ad0343dfc479f80b50dc1f26e81302021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-88513-zhttps://doaj.org/toc/2045-2322Abstract Mandibular cortical and trabecular bone abnormalities in patients with familial adenomatous polyposis (FAP) were evaluated using dental panoramic radiographs (DPR) radiomorphometric indices and fractal dimension (FD). Sixty DPRs from 15 FAP patients and 45 healthy controls were evaluated. FAP group was composed of 33.3% females and 66.6% males, agemean = 37.2 years (SD 15.79). The non-FAP group was paired by gender and sex. The parameters analyzed were: FD of the trabecular bone in four regions of interest (ROI), mandibular cortical index (MCI) and width (MCW). FD values were lower for the FAP group. Statistically significance differences were shown by ROI 2 and 3 anteriorly to the mental foramen bilaterally, p = 0.001, and p = 0.006. The ROI 1 and 4, at the mandibular angle trabeculae, indicated statistical significances on the right side (p = 0.036) and no differences on the left side (p = 0.091). There was no significant difference in MCI and MCW when the groups were compared, MCW (L) p = 0.247, and MCW (R) p = 0.070. Fractal values of FAP patients' mandibular trabecular bone were lower than healthy controls. The radiomorphometric indices MCI and MCW were not useful for analyzing the cortical bone pattern. Therefore, FD is a promising tool for detection of abnormal bone structure in DPRs and for supporting the appropriate referral of FAP patients.Camila Pacheco-PereiraYuri Silvestre-BarbosaFabiana T. AlmeidaHassem GehaAndre F. LeiteEliete N. S. GuerraNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Camila Pacheco-Pereira Yuri Silvestre-Barbosa Fabiana T. Almeida Hassem Geha Andre F. Leite Eliete N. S. Guerra Trabecular and cortical mandibular bone investigation in familial adenomatous polyposis patients
description	Abstract Mandibular cortical and trabecular bone abnormalities in patients with familial adenomatous polyposis (FAP) were evaluated using dental panoramic radiographs (DPR) radiomorphometric indices and fractal dimension (FD). Sixty DPRs from 15 FAP patients and 45 healthy controls were evaluated. FAP group was composed of 33.3% females and 66.6% males, agemean = 37.2 years (SD 15.79). The non-FAP group was paired by gender and sex. The parameters analyzed were: FD of the trabecular bone in four regions of interest (ROI), mandibular cortical index (MCI) and width (MCW). FD values were lower for the FAP group. Statistically significance differences were shown by ROI 2 and 3 anteriorly to the mental foramen bilaterally, p = 0.001, and p = 0.006. The ROI 1 and 4, at the mandibular angle trabeculae, indicated statistical significances on the right side (p = 0.036) and no differences on the left side (p = 0.091). There was no significant difference in MCI and MCW when the groups were compared, MCW (L) p = 0.247, and MCW (R) p = 0.070. Fractal values of FAP patients' mandibular trabecular bone were lower than healthy controls. The radiomorphometric indices MCI and MCW were not useful for analyzing the cortical bone pattern. Therefore, FD is a promising tool for detection of abnormal bone structure in DPRs and for supporting the appropriate referral of FAP patients.
format	article
author	Camila Pacheco-Pereira Yuri Silvestre-Barbosa Fabiana T. Almeida Hassem Geha Andre F. Leite Eliete N. S. Guerra
author_facet	Camila Pacheco-Pereira Yuri Silvestre-Barbosa Fabiana T. Almeida Hassem Geha Andre F. Leite Eliete N. S. Guerra
author_sort	Camila Pacheco-Pereira
title	Trabecular and cortical mandibular bone investigation in familial adenomatous polyposis patients
title_short	Trabecular and cortical mandibular bone investigation in familial adenomatous polyposis patients
title_full	Trabecular and cortical mandibular bone investigation in familial adenomatous polyposis patients
title_fullStr	Trabecular and cortical mandibular bone investigation in familial adenomatous polyposis patients
title_full_unstemmed	Trabecular and cortical mandibular bone investigation in familial adenomatous polyposis patients
title_sort	trabecular and cortical mandibular bone investigation in familial adenomatous polyposis patients
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/796ad0343dfc479f80b50dc1f26e8130
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Trabecular and cortical mandibular bone investigation in familial adenomatous polyposis patients

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