Single-molecule, full-length transcript isoform sequencing reveals disease-associated RNA isoforms in cardiomyocytes

Alternative splicing generates RNA isoforms that contribute to phenotypic diversity. Here the authors perform single-molecule full-length RNA sequencing to identify disease-associated variant transcript isoforms.

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Autores principales:	Chenchen Zhu, Jingyan Wu, Han Sun, Francesca Briganti, Benjamin Meder, Wu Wei, Lars M. Steinmetz
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/796f7f739d9e4d878b956c8f667091c3
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spelling	oai:doaj.org-article:796f7f739d9e4d878b956c8f667091c32021-12-02T15:39:43ZSingle-molecule, full-length transcript isoform sequencing reveals disease-associated RNA isoforms in cardiomyocytes10.1038/s41467-021-24484-z2041-1723https://doaj.org/article/796f7f739d9e4d878b956c8f667091c32021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24484-zhttps://doaj.org/toc/2041-1723Alternative splicing generates RNA isoforms that contribute to phenotypic diversity. Here the authors perform single-molecule full-length RNA sequencing to identify disease-associated variant transcript isoforms.Chenchen ZhuJingyan WuHan SunFrancesca BrigantiBenjamin MederWu WeiLars M. SteinmetzNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chenchen Zhu Jingyan Wu Han Sun Francesca Briganti Benjamin Meder Wu Wei Lars M. Steinmetz Single-molecule, full-length transcript isoform sequencing reveals disease-associated RNA isoforms in cardiomyocytes
description	Alternative splicing generates RNA isoforms that contribute to phenotypic diversity. Here the authors perform single-molecule full-length RNA sequencing to identify disease-associated variant transcript isoforms.
format	article
author	Chenchen Zhu Jingyan Wu Han Sun Francesca Briganti Benjamin Meder Wu Wei Lars M. Steinmetz
author_facet	Chenchen Zhu Jingyan Wu Han Sun Francesca Briganti Benjamin Meder Wu Wei Lars M. Steinmetz
author_sort	Chenchen Zhu
title	Single-molecule, full-length transcript isoform sequencing reveals disease-associated RNA isoforms in cardiomyocytes
title_short	Single-molecule, full-length transcript isoform sequencing reveals disease-associated RNA isoforms in cardiomyocytes
title_full	Single-molecule, full-length transcript isoform sequencing reveals disease-associated RNA isoforms in cardiomyocytes
title_fullStr	Single-molecule, full-length transcript isoform sequencing reveals disease-associated RNA isoforms in cardiomyocytes
title_full_unstemmed	Single-molecule, full-length transcript isoform sequencing reveals disease-associated RNA isoforms in cardiomyocytes
title_sort	single-molecule, full-length transcript isoform sequencing reveals disease-associated rna isoforms in cardiomyocytes
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/796f7f739d9e4d878b956c8f667091c3
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Single-molecule, full-length transcript isoform sequencing reveals disease-associated RNA isoforms in cardiomyocytes

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