Murine hematopoietic stem cell activity is derived from pre-circulation embryos but not yolk sacs

The source of where definitive hematopoietic stem cells (dHSCs) develop in the mouse embyro has been much debated. Here, the authors identify that dHSCs arise from the intra-embyronic region by using murine embryonic explant transplantation but not from the yolk sac.

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Autores principales:	Miguel Ganuza, Ashley Chabot, Xing Tang, Wenjian Bi, Sivaraman Natarajan, Robert Carter, Charles Gawad, Guolian Kang, Yong Cheng, Shannon McKinney-Freeman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7973eb1e655f4fbfabc98a89df0a89fe
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spelling	oai:doaj.org-article:7973eb1e655f4fbfabc98a89df0a89fe2021-12-02T16:56:54ZMurine hematopoietic stem cell activity is derived from pre-circulation embryos but not yolk sacs10.1038/s41467-018-07769-82041-1723https://doaj.org/article/7973eb1e655f4fbfabc98a89df0a89fe2018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07769-8https://doaj.org/toc/2041-1723The source of where definitive hematopoietic stem cells (dHSCs) develop in the mouse embyro has been much debated. Here, the authors identify that dHSCs arise from the intra-embyronic region by using murine embryonic explant transplantation but not from the yolk sac.Miguel GanuzaAshley ChabotXing TangWenjian BiSivaraman NatarajanRobert CarterCharles GawadGuolian KangYong ChengShannon McKinney-FreemanNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Miguel Ganuza Ashley Chabot Xing Tang Wenjian Bi Sivaraman Natarajan Robert Carter Charles Gawad Guolian Kang Yong Cheng Shannon McKinney-Freeman Murine hematopoietic stem cell activity is derived from pre-circulation embryos but not yolk sacs
description	The source of where definitive hematopoietic stem cells (dHSCs) develop in the mouse embyro has been much debated. Here, the authors identify that dHSCs arise from the intra-embyronic region by using murine embryonic explant transplantation but not from the yolk sac.
format	article
author	Miguel Ganuza Ashley Chabot Xing Tang Wenjian Bi Sivaraman Natarajan Robert Carter Charles Gawad Guolian Kang Yong Cheng Shannon McKinney-Freeman
author_facet	Miguel Ganuza Ashley Chabot Xing Tang Wenjian Bi Sivaraman Natarajan Robert Carter Charles Gawad Guolian Kang Yong Cheng Shannon McKinney-Freeman
author_sort	Miguel Ganuza
title	Murine hematopoietic stem cell activity is derived from pre-circulation embryos but not yolk sacs
title_short	Murine hematopoietic stem cell activity is derived from pre-circulation embryos but not yolk sacs
title_full	Murine hematopoietic stem cell activity is derived from pre-circulation embryos but not yolk sacs
title_fullStr	Murine hematopoietic stem cell activity is derived from pre-circulation embryos but not yolk sacs
title_full_unstemmed	Murine hematopoietic stem cell activity is derived from pre-circulation embryos but not yolk sacs
title_sort	murine hematopoietic stem cell activity is derived from pre-circulation embryos but not yolk sacs
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/7973eb1e655f4fbfabc98a89df0a89fe
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Murine hematopoietic stem cell activity is derived from pre-circulation embryos but not yolk sacs

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