Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studies

Shortening of leukocyte telomere length (LTL) is associated with age and increased risk for various chronic diseases. Here, the authors report genome-wide association studies for LTL in Singaporean Chinese populations and find that longer LTL associates with less severe outcomes of respiratory disea...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Rajkumar Dorajoo, Xuling Chang, Resham Lal Gurung, Zheng Li, Ling Wang, Renwei Wang, Kenneth B. Beckman, Jennifer Adams-Haduch, Yiamunaa M, Sylvia Liu, Wee Yang Meah, Kar Seng Sim, Su Chi Lim, Yechiel Friedlander, Jianjun Liu, Rob M. van Dam, Jian-Min Yuan, Woon-Puay Koh, Chiea Chuen Khor, Chew-Kiat Heng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/798819afb9664632abd7ea8734efd972
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:798819afb9664632abd7ea8734efd972
record_format	dspace
spelling	oai:doaj.org-article:798819afb9664632abd7ea8734efd9722021-12-02T17:01:33ZLoci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studies10.1038/s41467-019-10443-22041-1723https://doaj.org/article/798819afb9664632abd7ea8734efd9722019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10443-2https://doaj.org/toc/2041-1723Shortening of leukocyte telomere length (LTL) is associated with age and increased risk for various chronic diseases. Here, the authors report genome-wide association studies for LTL in Singaporean Chinese populations and find that longer LTL associates with less severe outcomes of respiratory disease phenotypes.Rajkumar DorajooXuling ChangResham Lal GurungZheng LiLing WangRenwei WangKenneth B. BeckmanJennifer Adams-HaduchYiamunaa MSylvia LiuWee Yang MeahKar Seng SimSu Chi LimYechiel FriedlanderJianjun LiuRob M. van DamJian-Min YuanWoon-Puay KohChiea Chuen KhorChew-Kiat HengNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rajkumar Dorajoo Xuling Chang Resham Lal Gurung Zheng Li Ling Wang Renwei Wang Kenneth B. Beckman Jennifer Adams-Haduch Yiamunaa M Sylvia Liu Wee Yang Meah Kar Seng Sim Su Chi Lim Yechiel Friedlander Jianjun Liu Rob M. van Dam Jian-Min Yuan Woon-Puay Koh Chiea Chuen Khor Chew-Kiat Heng Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studies
description	Shortening of leukocyte telomere length (LTL) is associated with age and increased risk for various chronic diseases. Here, the authors report genome-wide association studies for LTL in Singaporean Chinese populations and find that longer LTL associates with less severe outcomes of respiratory disease phenotypes.
format	article
author	Rajkumar Dorajoo Xuling Chang Resham Lal Gurung Zheng Li Ling Wang Renwei Wang Kenneth B. Beckman Jennifer Adams-Haduch Yiamunaa M Sylvia Liu Wee Yang Meah Kar Seng Sim Su Chi Lim Yechiel Friedlander Jianjun Liu Rob M. van Dam Jian-Min Yuan Woon-Puay Koh Chiea Chuen Khor Chew-Kiat Heng
author_facet	Rajkumar Dorajoo Xuling Chang Resham Lal Gurung Zheng Li Ling Wang Renwei Wang Kenneth B. Beckman Jennifer Adams-Haduch Yiamunaa M Sylvia Liu Wee Yang Meah Kar Seng Sim Su Chi Lim Yechiel Friedlander Jianjun Liu Rob M. van Dam Jian-Min Yuan Woon-Puay Koh Chiea Chuen Khor Chew-Kiat Heng
author_sort	Rajkumar Dorajoo
title	Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studies
title_short	Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studies
title_full	Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studies
title_fullStr	Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studies
title_full_unstemmed	Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studies
title_sort	loci for human leukocyte telomere length in the singaporean chinese population and trans-ethnic genetic studies
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/798819afb9664632abd7ea8734efd972
work_keys_str_mv	AT rajkumardorajoo lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies AT xulingchang lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies AT reshamlalgurung lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies AT zhengli lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies AT lingwang lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies AT renweiwang lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies AT kennethbbeckman lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies AT jenniferadamshaduch lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies AT yiamunaam lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies AT sylvialiu lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies AT weeyangmeah lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies AT karsengsim lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies AT suchilim lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies AT yechielfriedlander lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies AT jianjunliu lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies AT robmvandam lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies AT jianminyuan lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies AT woonpuaykoh lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies AT chieachuenkhor lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies AT chewkiatheng lociforhumanleukocytetelomerelengthinthesingaporeanchinesepopulationandtransethnicgeneticstudies
_version_	1718382090985144320

Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studies

Ejemplares similares