Epidermal control of axonal attachment via β-spectrin and the GTPase-activating protein TBC-10 prevents axonal degeneration
Neurons are subjected to strains due to body movements and their locations within organs and tissues. Here the authors show that UNC-70/β-spectrin and TBC-10 dynamically maintain attachment of the axon within the epidermis non-cell-autonomously by stabilizing hemidesmosome attachment, preventing axo...
Guardado en:
Autores principales: | Sean Coakley, Fiona K. Ritchie, Kate M. Galbraith, Massimo A. Hilliard |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/7988a664ddb54a37b81626780cf423c1 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Protective Effect of Hyperbaric Oxygen Treatment on Axon Degeneration after Acute Motor Axonal Neuropathy
por: Ni Komang Sri Dewi Untari, et al.
Publicado: (2021) -
Delayed glial clearance of degenerating axons in aged Drosophila is due to reduced PI3K/Draper activity
por: Maria D. Purice, et al.
Publicado: (2016) -
Myelination, axonal loss and Schwann cell characteristics in axonal polyneuropathy compared to controls.
por: Eva Placheta-Györi, et al.
Publicado: (2021) -
Myelination, axonal loss and Schwann cell characteristics in axonal polyneuropathy compared to controls
por: Eva Placheta-Györi, et al.
Publicado: (2021) -
Axon degeneration induces glial responses through Draper-TRAF4-JNK signalling
por: Tsai-Yi Lu, et al.
Publicado: (2017)