Extraocular sebaceous carcinoma: a series of three cases with varied presentation

Background: Extraocular sebaceous carcinomas are rare cutaneous malignancies that account for only about 25% of all sebaceous carcinomas. The most common site of occurrence is the head/neck region. They are aggressive neoplasms that possess metastatic potential to regional or distant sites. Wide lo...

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Autores principales:	Poonam K. Panjwani, Rajalakshmi Tirumalae, Julian Castra, Suraj Manjunath, Pritilata Rout
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2012
Materias:	sebaceous carcinoma extraocular Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/79910c7cc8b541039b36777d567734af
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spelling	oai:doaj.org-article:79910c7cc8b541039b36777d567734af2021-11-17T08:33:15ZExtraocular sebaceous carcinoma: a series of three cases with varied presentation10.5826/dpc.0201a072160-9381https://doaj.org/article/79910c7cc8b541039b36777d567734af2012-01-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/1150https://doaj.org/toc/2160-9381 Background: Extraocular sebaceous carcinomas are rare cutaneous malignancies that account for only about 25% of all sebaceous carcinomas. The most common site of occurrence is the head/neck region. They are aggressive neoplasms that possess metastatic potential to regional or distant sites. Wide local excision of the lesion with removal of regional lymph nodes is the usual mode of therapy. Methods: We present a series of three cases of sebaceous carcinomas occurring in extraocular sites outside the head and neck areas, like the axilla, chest wall, arm and thigh. One of these cases had an associated colonic carcinoma and constituted Muir-Torre syndrome (MTS). Another case presented with a skin nodule and regional nodal metastasis. The third case had a history of recurrent similar lesions at the same site. Conclusion: Although rare, extraocular sebaceous carcinomas are seen at varied sites and frequently pose problems in diagnosis. A longterm follow-up of these cases is warranted due to their aggressive behaviour, risks of recurrence, metastasis and the possibility of development of visceral malignancies. Poonam K. PanjwaniRajalakshmi TirumalaeJulian CastraSuraj ManjunathPritilata RoutMattioli1885articlesebaceous carcinomaextraocularDermatologyRL1-803ENDermatology Practical & Conceptual (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	sebaceous carcinoma extraocular Dermatology RL1-803
spellingShingle	sebaceous carcinoma extraocular Dermatology RL1-803 Poonam K. Panjwani Rajalakshmi Tirumalae Julian Castra Suraj Manjunath Pritilata Rout Extraocular sebaceous carcinoma: a series of three cases with varied presentation
description	Background: Extraocular sebaceous carcinomas are rare cutaneous malignancies that account for only about 25% of all sebaceous carcinomas. The most common site of occurrence is the head/neck region. They are aggressive neoplasms that possess metastatic potential to regional or distant sites. Wide local excision of the lesion with removal of regional lymph nodes is the usual mode of therapy. Methods: We present a series of three cases of sebaceous carcinomas occurring in extraocular sites outside the head and neck areas, like the axilla, chest wall, arm and thigh. One of these cases had an associated colonic carcinoma and constituted Muir-Torre syndrome (MTS). Another case presented with a skin nodule and regional nodal metastasis. The third case had a history of recurrent similar lesions at the same site. Conclusion: Although rare, extraocular sebaceous carcinomas are seen at varied sites and frequently pose problems in diagnosis. A longterm follow-up of these cases is warranted due to their aggressive behaviour, risks of recurrence, metastasis and the possibility of development of visceral malignancies.
format	article
author	Poonam K. Panjwani Rajalakshmi Tirumalae Julian Castra Suraj Manjunath Pritilata Rout
author_facet	Poonam K. Panjwani Rajalakshmi Tirumalae Julian Castra Suraj Manjunath Pritilata Rout
author_sort	Poonam K. Panjwani
title	Extraocular sebaceous carcinoma: a series of three cases with varied presentation
title_short	Extraocular sebaceous carcinoma: a series of three cases with varied presentation
title_full	Extraocular sebaceous carcinoma: a series of three cases with varied presentation
title_fullStr	Extraocular sebaceous carcinoma: a series of three cases with varied presentation
title_full_unstemmed	Extraocular sebaceous carcinoma: a series of three cases with varied presentation
title_sort	extraocular sebaceous carcinoma: a series of three cases with varied presentation
publisher	Mattioli1885
publishDate	2012
url	https://doaj.org/article/79910c7cc8b541039b36777d567734af
work_keys_str_mv	AT poonamkpanjwani extraocularsebaceouscarcinomaaseriesofthreecaseswithvariedpresentation AT rajalakshmitirumalae extraocularsebaceouscarcinomaaseriesofthreecaseswithvariedpresentation AT juliancastra extraocularsebaceouscarcinomaaseriesofthreecaseswithvariedpresentation AT surajmanjunath extraocularsebaceouscarcinomaaseriesofthreecaseswithvariedpresentation AT pritilatarout extraocularsebaceouscarcinomaaseriesofthreecaseswithvariedpresentation
_version_	1718425680478208000

Extraocular sebaceous carcinoma: a series of three cases with varied presentation

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