Dietary fatty acids fine-tune Piezo1 mechanical response

Piezo channels are mechanosensitive and rely on membrane composition to transduce physical stimuli into electrical signals. Here authors analyse the membrane components that modulate Piezo1 function using lipid profiling which shows that fatty acid metabolism can modulate ion channel activity.

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Autores principales:	Luis O. Romero, Andrew E. Massey, Alejandro D. Mata-Daboin, Francisco J. Sierra-Valdez, Subhash C. Chauhan, Julio F. Cordero-Morales, Valeria Vásquez
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/79b47773086f40d2b56953992c83ae64
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spelling	oai:doaj.org-article:79b47773086f40d2b56953992c83ae642021-12-02T15:35:51ZDietary fatty acids fine-tune Piezo1 mechanical response10.1038/s41467-019-09055-72041-1723https://doaj.org/article/79b47773086f40d2b56953992c83ae642019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09055-7https://doaj.org/toc/2041-1723Piezo channels are mechanosensitive and rely on membrane composition to transduce physical stimuli into electrical signals. Here authors analyse the membrane components that modulate Piezo1 function using lipid profiling which shows that fatty acid metabolism can modulate ion channel activity.Luis O. RomeroAndrew E. MasseyAlejandro D. Mata-DaboinFrancisco J. Sierra-ValdezSubhash C. ChauhanJulio F. Cordero-MoralesValeria VásquezNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Luis O. Romero Andrew E. Massey Alejandro D. Mata-Daboin Francisco J. Sierra-Valdez Subhash C. Chauhan Julio F. Cordero-Morales Valeria Vásquez Dietary fatty acids fine-tune Piezo1 mechanical response
description	Piezo channels are mechanosensitive and rely on membrane composition to transduce physical stimuli into electrical signals. Here authors analyse the membrane components that modulate Piezo1 function using lipid profiling which shows that fatty acid metabolism can modulate ion channel activity.
format	article
author	Luis O. Romero Andrew E. Massey Alejandro D. Mata-Daboin Francisco J. Sierra-Valdez Subhash C. Chauhan Julio F. Cordero-Morales Valeria Vásquez
author_facet	Luis O. Romero Andrew E. Massey Alejandro D. Mata-Daboin Francisco J. Sierra-Valdez Subhash C. Chauhan Julio F. Cordero-Morales Valeria Vásquez
author_sort	Luis O. Romero
title	Dietary fatty acids fine-tune Piezo1 mechanical response
title_short	Dietary fatty acids fine-tune Piezo1 mechanical response
title_full	Dietary fatty acids fine-tune Piezo1 mechanical response
title_fullStr	Dietary fatty acids fine-tune Piezo1 mechanical response
title_full_unstemmed	Dietary fatty acids fine-tune Piezo1 mechanical response
title_sort	dietary fatty acids fine-tune piezo1 mechanical response
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/79b47773086f40d2b56953992c83ae64
work_keys_str_mv	AT luisoromero dietaryfattyacidsfinetunepiezo1mechanicalresponse AT andrewemassey dietaryfattyacidsfinetunepiezo1mechanicalresponse AT alejandrodmatadaboin dietaryfattyacidsfinetunepiezo1mechanicalresponse AT franciscojsierravaldez dietaryfattyacidsfinetunepiezo1mechanicalresponse AT subhashcchauhan dietaryfattyacidsfinetunepiezo1mechanicalresponse AT juliofcorderomorales dietaryfattyacidsfinetunepiezo1mechanicalresponse AT valeriavasquez dietaryfattyacidsfinetunepiezo1mechanicalresponse
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Dietary fatty acids fine-tune Piezo1 mechanical response

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