IFITM3 inhibits influenza A virus infection by preventing cytosolic entry.
To replicate, viruses must gain access to the host cell's resources. Interferon (IFN) regulates the actions of a large complement of interferon effector genes (IEGs) that prevent viral replication. The interferon inducible transmembrane protein family members, IFITM1, 2 and 3, are IEGs required...
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Autores principales: | Eric M Feeley, Jennifer S Sims, Sinu P John, Christopher R Chin, Thomas Pertel, Li-Mei Chen, Gaurav D Gaiha, Bethany J Ryan, Ruben O Donis, Stephen J Elledge, Abraham L Brass |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/79b4c2d4af1b4f7d9ea4310cc58480f8 |
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