IFITM3 inhibits influenza A virus infection by preventing cytosolic entry.
To replicate, viruses must gain access to the host cell's resources. Interferon (IFN) regulates the actions of a large complement of interferon effector genes (IEGs) that prevent viral replication. The interferon inducible transmembrane protein family members, IFITM1, 2 and 3, are IEGs required...
Saved in:
Main Authors: | Eric M Feeley, Jennifer S Sims, Sinu P John, Christopher R Chin, Thomas Pertel, Li-Mei Chen, Gaurav D Gaiha, Bethany J Ryan, Ruben O Donis, Stephen J Elledge, Abraham L Brass |
---|---|
Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2011
|
Subjects: | |
Online Access: | https://doaj.org/article/79b4c2d4af1b4f7d9ea4310cc58480f8 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
IFITM proteins restrict viral membrane hemifusion.
by: Kun Li, et al.
Published: (2013) -
A novel probe to assess cytosolic entry of exogenous proteins
by: Qiao Lu, et al.
Published: (2018) -
Listeria exploits IFITM3 to suppress antibacterial activity in phagocytes
by: Joel M. J. Tan, et al.
Published: (2021) -
IFITM3 Reduces Retroviral Envelope Abundance and Function and Is Counteracted by glycoGag
by: Yadvinder S. Ahi, et al.
Published: (2020) -
IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro
by: Caterina Prelli Bozzo, et al.
Published: (2021)