Characteristics of Somatic Status and Individual Biochemical Markers in Patients with Retinal Vein Occlusion

Retinal vein occlusion is one of the most severe vascular lesions of the organ of vision, usually accompanied by somatic pathology.The aim of the study was to study the somatic status and individual biochemical markers in patients with retinal vein occlusion and comparison in groups opposing the eff...

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Autores principales:	I. V. Zlobin, T. N. Iureva, Yu. V. Kursakova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2019
Materias:	retinal vein occlusion somatic status arterial hypertension anti-vegf therapy ranibizumab Science Q
Acceso en línea:	https://doaj.org/article/79b9cb03548d443cb6337480c3eed96f
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spelling	oai:doaj.org-article:79b9cb03548d443cb6337480c3eed96f2021-11-23T06:14:43ZCharacteristics of Somatic Status and Individual Biochemical Markers in Patients with Retinal Vein Occlusion2541-94202587-959610.29413/ABS.2019-4.4.24https://doaj.org/article/79b9cb03548d443cb6337480c3eed96f2019-08-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/2138https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Retinal vein occlusion is one of the most severe vascular lesions of the organ of vision, usually accompanied by somatic pathology.The aim of the study was to study the somatic status and individual biochemical markers in patients with retinal vein occlusion and comparison in groups opposing the effectiveness of anti-VEGF therapy.Methods. 84 patients with macular edema were examined on the background of retinal vein occlusion, who underwent intravitreal injections of an angiogenesis inhibitor for therapeutic purposes. Further, depending on the effectiveness of treatment, the patients were divided into 2 groups, in which a retrospective comparative analysis of somatic status and laboratory data was performed.Results. It was shown that patients with occlusion of the retinal veins have significant impairments in terms of somatic status, blood biochemical parameters and coagulogram. Moreover, there is a direct relationship between the severity of somatic changes and ocular manifestations of the disease. The data obtained reflect a clear tendency in patients with occlusion of the retinal veins to a high risk of cardiovascular complications, including occlusive lesions. In patients with an insufficient treatment effect, a more severe course of arterial hypertension with an increased risk of stratification was detected.Conclusion. The somatic status and laboratory parameters of patients with retinal vein occlusion are significantly different from the norm, which must be taken into account in the prognosis of the course of an ophthalmologic disease.I. V. ZlobinT. N. IurevaYu. V. KursakovaScientific Сentre for Family Health and Human Reproduction Problemsarticleretinal vein occlusionretinal vein occlusionsomatic statusarterial hypertensionanti-vegf therapyranibizumabScienceQRUActa Biomedica Scientifica, Vol 4, Iss 4, Pp 150-156 (2019)
institution	DOAJ
collection	DOAJ
language	RU
topic	retinal vein occlusion retinal vein occlusion somatic status arterial hypertension anti-vegf therapy ranibizumab Science Q
spellingShingle	retinal vein occlusion retinal vein occlusion somatic status arterial hypertension anti-vegf therapy ranibizumab Science Q I. V. Zlobin T. N. Iureva Yu. V. Kursakova Characteristics of Somatic Status and Individual Biochemical Markers in Patients with Retinal Vein Occlusion
description	Retinal vein occlusion is one of the most severe vascular lesions of the organ of vision, usually accompanied by somatic pathology.The aim of the study was to study the somatic status and individual biochemical markers in patients with retinal vein occlusion and comparison in groups opposing the effectiveness of anti-VEGF therapy.Methods. 84 patients with macular edema were examined on the background of retinal vein occlusion, who underwent intravitreal injections of an angiogenesis inhibitor for therapeutic purposes. Further, depending on the effectiveness of treatment, the patients were divided into 2 groups, in which a retrospective comparative analysis of somatic status and laboratory data was performed.Results. It was shown that patients with occlusion of the retinal veins have significant impairments in terms of somatic status, blood biochemical parameters and coagulogram. Moreover, there is a direct relationship between the severity of somatic changes and ocular manifestations of the disease. The data obtained reflect a clear tendency in patients with occlusion of the retinal veins to a high risk of cardiovascular complications, including occlusive lesions. In patients with an insufficient treatment effect, a more severe course of arterial hypertension with an increased risk of stratification was detected.Conclusion. The somatic status and laboratory parameters of patients with retinal vein occlusion are significantly different from the norm, which must be taken into account in the prognosis of the course of an ophthalmologic disease.
format	article
author	I. V. Zlobin T. N. Iureva Yu. V. Kursakova
author_facet	I. V. Zlobin T. N. Iureva Yu. V. Kursakova
author_sort	I. V. Zlobin
title	Characteristics of Somatic Status and Individual Biochemical Markers in Patients with Retinal Vein Occlusion
title_short	Characteristics of Somatic Status and Individual Biochemical Markers in Patients with Retinal Vein Occlusion
title_full	Characteristics of Somatic Status and Individual Biochemical Markers in Patients with Retinal Vein Occlusion
title_fullStr	Characteristics of Somatic Status and Individual Biochemical Markers in Patients with Retinal Vein Occlusion
title_full_unstemmed	Characteristics of Somatic Status and Individual Biochemical Markers in Patients with Retinal Vein Occlusion
title_sort	characteristics of somatic status and individual biochemical markers in patients with retinal vein occlusion
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2019
url	https://doaj.org/article/79b9cb03548d443cb6337480c3eed96f
work_keys_str_mv	AT ivzlobin characteristicsofsomaticstatusandindividualbiochemicalmarkersinpatientswithretinalveinocclusion AT tniureva characteristicsofsomaticstatusandindividualbiochemicalmarkersinpatientswithretinalveinocclusion AT yuvkursakova characteristicsofsomaticstatusandindividualbiochemicalmarkersinpatientswithretinalveinocclusion
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Characteristics of Somatic Status and Individual Biochemical Markers in Patients with Retinal Vein Occlusion

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