Association Study on Nutrition in the First Year of Life and Molar-Incisor Hypomineralization (MIH)—Results from the GINIplus and LISA Birth Cohort Studies

Molar-incisor hypomineralization (MIH) is a condition with specific clinical presentation whose etiology to date still remains unknown. This study prospectively investigated the association between nutrition during the 1st year of life and the presence of MIH in the permanent dentition. Data from 10...

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Autores principales:	Yeganeh Khazaei, Carla P. Harris, Joachim Heinrich, Marie Standl, Jan Kühnisch
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	molar-incisor hypomineralization developmental enamel defects early nutrition exclusive breastfeeding birth cohort study epidemiology Medicine R
Acceso en línea:	https://doaj.org/article/79bdfd4d75a446b99b7eb9bfde15c113
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spelling	oai:doaj.org-article:79bdfd4d75a446b99b7eb9bfde15c1132021-11-11T16:31:24ZAssociation Study on Nutrition in the First Year of Life and Molar-Incisor Hypomineralization (MIH)—Results from the GINIplus and LISA Birth Cohort Studies10.3390/ijerph1821114111660-46011661-7827https://doaj.org/article/79bdfd4d75a446b99b7eb9bfde15c1132021-10-01T00:00:00Zhttps://www.mdpi.com/1660-4601/18/21/11411https://doaj.org/toc/1661-7827https://doaj.org/toc/1660-4601Molar-incisor hypomineralization (MIH) is a condition with specific clinical presentation whose etiology to date still remains unknown. This study prospectively investigated the association between nutrition during the 1st year of life and the presence of MIH in the permanent dentition. Data from 1070 10-year-old children from two prospective birth cohort studies were included. Information on exclusive breastfeeding (EBF) and introduction of 48 food items into the child’s diet was assessed at 4-, 6-, and 12-month time-points. Food diversity was defined according to the number of food items or food groups introduced into the child’s diet and then subsequent categorization into low-, middle- and high-diversity groups was performed. MIH was scored in the permanent dentition at age of 10 years. The statistical analysis included logistic and Poisson hurdle regression models adjusted for potential confounders. EBF, food item and food group diversity at 4-, 6-, 12-month time-points were found to be non-significant in most of the categories for the development of MIH. However, significantly higher odds for the presence of MIH were found for certain categories. Despite the limitation of this study, such as arbitrary cut-offs for categorization of food items, the results of this study suggest the lack of an association between early nutrition in the first year of life and MIH in the permanent dentition.Yeganeh KhazaeiCarla P. HarrisJoachim HeinrichMarie StandlJan KühnischMDPI AGarticlemolar-incisor hypomineralizationdevelopmental enamel defectsearly nutritionexclusive breastfeedingbirth cohort studyepidemiologyMedicineRENInternational Journal of Environmental Research and Public Health, Vol 18, Iss 11411, p 11411 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	molar-incisor hypomineralization developmental enamel defects early nutrition exclusive breastfeeding birth cohort study epidemiology Medicine R
spellingShingle	molar-incisor hypomineralization developmental enamel defects early nutrition exclusive breastfeeding birth cohort study epidemiology Medicine R Yeganeh Khazaei Carla P. Harris Joachim Heinrich Marie Standl Jan Kühnisch Association Study on Nutrition in the First Year of Life and Molar-Incisor Hypomineralization (MIH)—Results from the GINIplus and LISA Birth Cohort Studies
description	Molar-incisor hypomineralization (MIH) is a condition with specific clinical presentation whose etiology to date still remains unknown. This study prospectively investigated the association between nutrition during the 1st year of life and the presence of MIH in the permanent dentition. Data from 1070 10-year-old children from two prospective birth cohort studies were included. Information on exclusive breastfeeding (EBF) and introduction of 48 food items into the child’s diet was assessed at 4-, 6-, and 12-month time-points. Food diversity was defined according to the number of food items or food groups introduced into the child’s diet and then subsequent categorization into low-, middle- and high-diversity groups was performed. MIH was scored in the permanent dentition at age of 10 years. The statistical analysis included logistic and Poisson hurdle regression models adjusted for potential confounders. EBF, food item and food group diversity at 4-, 6-, 12-month time-points were found to be non-significant in most of the categories for the development of MIH. However, significantly higher odds for the presence of MIH were found for certain categories. Despite the limitation of this study, such as arbitrary cut-offs for categorization of food items, the results of this study suggest the lack of an association between early nutrition in the first year of life and MIH in the permanent dentition.
format	article
author	Yeganeh Khazaei Carla P. Harris Joachim Heinrich Marie Standl Jan Kühnisch
author_facet	Yeganeh Khazaei Carla P. Harris Joachim Heinrich Marie Standl Jan Kühnisch
author_sort	Yeganeh Khazaei
title	Association Study on Nutrition in the First Year of Life and Molar-Incisor Hypomineralization (MIH)—Results from the GINIplus and LISA Birth Cohort Studies
title_short	Association Study on Nutrition in the First Year of Life and Molar-Incisor Hypomineralization (MIH)—Results from the GINIplus and LISA Birth Cohort Studies
title_full	Association Study on Nutrition in the First Year of Life and Molar-Incisor Hypomineralization (MIH)—Results from the GINIplus and LISA Birth Cohort Studies
title_fullStr	Association Study on Nutrition in the First Year of Life and Molar-Incisor Hypomineralization (MIH)—Results from the GINIplus and LISA Birth Cohort Studies
title_full_unstemmed	Association Study on Nutrition in the First Year of Life and Molar-Incisor Hypomineralization (MIH)—Results from the GINIplus and LISA Birth Cohort Studies
title_sort	association study on nutrition in the first year of life and molar-incisor hypomineralization (mih)—results from the giniplus and lisa birth cohort studies
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/79bdfd4d75a446b99b7eb9bfde15c113
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Association Study on Nutrition in the First Year of Life and Molar-Incisor Hypomineralization (MIH)—Results from the GINIplus and LISA Birth Cohort Studies

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