ZFP30 promotes adipogenesis through the KAP1-mediated activation of a retrotransposon-derived Pparg2 enhancer
Although Krüppel-associated box zinc finger proteins (KZFPs) were found to mostly repress transposable elements, recent studies found that KFZPs also play other roles in cells. Here, the authors provide evidence that the KZFP ZFP30 promotes adipogenesis by targeting and activating a retrotransposon-...
Enregistré dans:
Auteurs principaux: | Wanze Chen, Petra C. Schwalie, Eugenia V. Pankevich, Carine Gubelmann, Sunil K. Raghav, Riccardo Dainese, Marco Cassano, Michael Imbeault, Suk Min Jang, Julie Russeil, Tenagne Delessa, Julien Duc, Didier Trono, Christian Wolfrum, Bart Deplancke |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/79c0840feab948d880b74c9fb3a62bf1 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
PPARG binding landscapes in macrophages suggest a genome-wide contribution of PU.1 to divergent PPARG binding in human and mouse.
par: Sebastian Pott, et autres
Publié: (2012) -
Association of FTO and PPARG polymorphisms with obesity in Portuguese women
par: Ferreira Carlos F, et autres
Publié: (2013) -
Inhibition of HIV-1 gene transcription by KAP1 in myeloid lineage
par: Amina Ait-Ammar, et autres
Publié: (2021) -
LTR retrotransposons in fungi.
par: Anna Muszewska, et autres
Publié: (2011) -
Adipogénesis y osteoporosis
par: Rodríguez,Juan Pablo, et autres
Publié: (2009)