Short-term outcomes of phosphodiesterase type 5 inhibitors for fetal growth restriction: a study protocol for a systematic review with individual participant data meta-analysis, aggregate meta-analysis, and trial sequential analysis
Abstract Background Early onset fetal growth restriction secondary to placental insufficiency can lead to severe maternal and neonatal morbidity and mortality. Pre-clinical studies and a few small randomised clinical trials have suggested that phosphodiesterase type 5 (PDE-5) inhibitors may have pro...
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Main Authors: | , , , , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
BMC
2021
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Subjects: | |
Online Access: | https://doaj.org/article/79c934a25fd948e0a218890e5020aafc |
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