Reducing split-thickness skin grafting donor site agony; faster healing and decreased pain-role of platelet-rich plasma

INTRODUCTION: The split-thickness skin graft harvested donor site is associated with prolonged healing, discomfort, and pain. Platelet-rich plasma (PRP) contains platelet-derived growth factors and has been widely used in chronic wounds and skin graft donor sites. PRP application is known to acceler...

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Autores principales:	Rakesh Kumar Jain, Ghisulal M Choudhary, Gajendra Gupta, Aditya N Patil, Gautam D Prakash, Ayush K Jain
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	platelet-rich plasma skin graft donor site dressing skin grafting Diseases of the blood and blood-forming organs RC633-647.5
Acceso en línea:	https://doaj.org/article/79cd03300eba4217aabcd814f6f9472c
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spelling	oai:doaj.org-article:79cd03300eba4217aabcd814f6f9472c2021-11-12T10:08:28ZReducing split-thickness skin grafting donor site agony; faster healing and decreased pain-role of platelet-rich plasma0973-62471998-356510.4103/ajts.AJTS_39_17https://doaj.org/article/79cd03300eba4217aabcd814f6f9472c2021-01-01T00:00:00Zhttp://www.ajts.org/article.asp?issn=0973-6247;year=2021;volume=15;issue=2;spage=195;epage=198;aulast=Jainhttps://doaj.org/toc/0973-6247https://doaj.org/toc/1998-3565INTRODUCTION: The split-thickness skin graft harvested donor site is associated with prolonged healing, discomfort, and pain. Platelet-rich plasma (PRP) contains platelet-derived growth factors and has been widely used in chronic wounds and skin graft donor sites. PRP application is known to accelerate wound epithelialization rates, and also reduce postoperative wound site pain.MATERIALS AND METHODS: We assessed 20 patients admitted to our hospital service who underwent split-thickness skin grafting (STSGs) with proximal half of the donor site treated with PRP. The dressing was conducted on postoperative day 7, 14, and 21. The donor site healing was assessed with serial photographs and donor site pain measured by numerical rating scale.RESULTS: Complete healing of wounds (epithelialization) was present in 12 (60%) patients dressed with PRP. Pain on opening dressing was an average of 3.5 in PRP dressed wounds and 6.35 in control wounds. Patients dressed without PRP, none of them had complete epithelialization. All patients had partial healing and were less than the donor site dressed with PRP. Based on these results, skin graft donor site with PRP showed accelerated healing and reduced pain and discomfort compared to control without PRP.CONCLUSION: PRP is a beneficial adjunct for reducing donor site pain and increased healing of donor site following STSG harvest.Rakesh Kumar JainGhisulal M ChoudharyGajendra GuptaAditya N PatilGautam D PrakashAyush K JainWolters Kluwer Medknow Publicationsarticleplatelet-rich plasmaskin graft donor site dressingskin graftingDiseases of the blood and blood-forming organsRC633-647.5ENAsian Journal of Transfusion Science, Vol 15, Iss 2, Pp 195-198 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	platelet-rich plasma skin graft donor site dressing skin grafting Diseases of the blood and blood-forming organs RC633-647.5
spellingShingle	platelet-rich plasma skin graft donor site dressing skin grafting Diseases of the blood and blood-forming organs RC633-647.5 Rakesh Kumar Jain Ghisulal M Choudhary Gajendra Gupta Aditya N Patil Gautam D Prakash Ayush K Jain Reducing split-thickness skin grafting donor site agony; faster healing and decreased pain-role of platelet-rich plasma
description	INTRODUCTION: The split-thickness skin graft harvested donor site is associated with prolonged healing, discomfort, and pain. Platelet-rich plasma (PRP) contains platelet-derived growth factors and has been widely used in chronic wounds and skin graft donor sites. PRP application is known to accelerate wound epithelialization rates, and also reduce postoperative wound site pain.MATERIALS AND METHODS: We assessed 20 patients admitted to our hospital service who underwent split-thickness skin grafting (STSGs) with proximal half of the donor site treated with PRP. The dressing was conducted on postoperative day 7, 14, and 21. The donor site healing was assessed with serial photographs and donor site pain measured by numerical rating scale.RESULTS: Complete healing of wounds (epithelialization) was present in 12 (60%) patients dressed with PRP. Pain on opening dressing was an average of 3.5 in PRP dressed wounds and 6.35 in control wounds. Patients dressed without PRP, none of them had complete epithelialization. All patients had partial healing and were less than the donor site dressed with PRP. Based on these results, skin graft donor site with PRP showed accelerated healing and reduced pain and discomfort compared to control without PRP.CONCLUSION: PRP is a beneficial adjunct for reducing donor site pain and increased healing of donor site following STSG harvest.
format	article
author	Rakesh Kumar Jain Ghisulal M Choudhary Gajendra Gupta Aditya N Patil Gautam D Prakash Ayush K Jain
author_facet	Rakesh Kumar Jain Ghisulal M Choudhary Gajendra Gupta Aditya N Patil Gautam D Prakash Ayush K Jain
author_sort	Rakesh Kumar Jain
title	Reducing split-thickness skin grafting donor site agony; faster healing and decreased pain-role of platelet-rich plasma
title_short	Reducing split-thickness skin grafting donor site agony; faster healing and decreased pain-role of platelet-rich plasma
title_full	Reducing split-thickness skin grafting donor site agony; faster healing and decreased pain-role of platelet-rich plasma
title_fullStr	Reducing split-thickness skin grafting donor site agony; faster healing and decreased pain-role of platelet-rich plasma
title_full_unstemmed	Reducing split-thickness skin grafting donor site agony; faster healing and decreased pain-role of platelet-rich plasma
title_sort	reducing split-thickness skin grafting donor site agony; faster healing and decreased pain-role of platelet-rich plasma
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/79cd03300eba4217aabcd814f6f9472c
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Reducing split-thickness skin grafting donor site agony; faster healing and decreased pain-role of platelet-rich plasma

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