Reverse Anti-solvent Crystallization Process for the Facile Synthesis of Zinc Tetra(4-pyridyl)porphyrin Single Crystalline Cubes

Abstract Synthesis of morphologically well-defined crystals of metalloporphyrin by direct crystallization based on conventional anti-solvent crystallization method without using any additives has been rarely reported. Herein, we demonstrate an unconventional and additive-free synthetic method named...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Yohwan Park, Misun Hong, Jin Young Koo, Minkyung Lee, Jinho Lee, Dae Jun Moon, So Hyeong Sohn, Taiha Joo, Woo Taik Lim, Hyunseob Lim, Hee Cheul Choi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/79d4664dbe5e46ad9b5bef7158b6c73d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:79d4664dbe5e46ad9b5bef7158b6c73d
record_format	dspace
spelling	oai:doaj.org-article:79d4664dbe5e46ad9b5bef7158b6c73d2021-12-02T15:04:59ZReverse Anti-solvent Crystallization Process for the Facile Synthesis of Zinc Tetra(4-pyridyl)porphyrin Single Crystalline Cubes10.1038/s41598-017-02718-92045-2322https://doaj.org/article/79d4664dbe5e46ad9b5bef7158b6c73d2017-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-02718-9https://doaj.org/toc/2045-2322Abstract Synthesis of morphologically well-defined crystals of metalloporphyrin by direct crystallization based on conventional anti-solvent crystallization method without using any additives has been rarely reported. Herein, we demonstrate an unconventional and additive-free synthetic method named reverse anti-solvent crystallization method to achieve well-defined zinc-porphyrin cube crystals by reversing the order of the addition of solvents. The extended first solvation shell effect mechanism is therefore suggested to support the synthetic process by providing a novel kinetic route for reaching the local supersaturation environment depending on the order of addition of solvents, which turned out to be critical to achieve clean cube morphology of the crystal. We believe that our work not only extends fundamental knowledge about the kinetic process in binary solvent systems, but also enables great opportunities for shape-directing crystallization of various organic and organometallic compounds.Yohwan ParkMisun HongJin Young KooMinkyung LeeJinho LeeDae Jun MoonSo Hyeong SohnTaiha JooWoo Taik LimHyunseob LimHee Cheul ChoiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Yohwan Park Misun Hong Jin Young Koo Minkyung Lee Jinho Lee Dae Jun Moon So Hyeong Sohn Taiha Joo Woo Taik Lim Hyunseob Lim Hee Cheul Choi Reverse Anti-solvent Crystallization Process for the Facile Synthesis of Zinc Tetra(4-pyridyl)porphyrin Single Crystalline Cubes
description	Abstract Synthesis of morphologically well-defined crystals of metalloporphyrin by direct crystallization based on conventional anti-solvent crystallization method without using any additives has been rarely reported. Herein, we demonstrate an unconventional and additive-free synthetic method named reverse anti-solvent crystallization method to achieve well-defined zinc-porphyrin cube crystals by reversing the order of the addition of solvents. The extended first solvation shell effect mechanism is therefore suggested to support the synthetic process by providing a novel kinetic route for reaching the local supersaturation environment depending on the order of addition of solvents, which turned out to be critical to achieve clean cube morphology of the crystal. We believe that our work not only extends fundamental knowledge about the kinetic process in binary solvent systems, but also enables great opportunities for shape-directing crystallization of various organic and organometallic compounds.
format	article
author	Yohwan Park Misun Hong Jin Young Koo Minkyung Lee Jinho Lee Dae Jun Moon So Hyeong Sohn Taiha Joo Woo Taik Lim Hyunseob Lim Hee Cheul Choi
author_facet	Yohwan Park Misun Hong Jin Young Koo Minkyung Lee Jinho Lee Dae Jun Moon So Hyeong Sohn Taiha Joo Woo Taik Lim Hyunseob Lim Hee Cheul Choi
author_sort	Yohwan Park
title	Reverse Anti-solvent Crystallization Process for the Facile Synthesis of Zinc Tetra(4-pyridyl)porphyrin Single Crystalline Cubes
title_short	Reverse Anti-solvent Crystallization Process for the Facile Synthesis of Zinc Tetra(4-pyridyl)porphyrin Single Crystalline Cubes
title_full	Reverse Anti-solvent Crystallization Process for the Facile Synthesis of Zinc Tetra(4-pyridyl)porphyrin Single Crystalline Cubes
title_fullStr	Reverse Anti-solvent Crystallization Process for the Facile Synthesis of Zinc Tetra(4-pyridyl)porphyrin Single Crystalline Cubes
title_full_unstemmed	Reverse Anti-solvent Crystallization Process for the Facile Synthesis of Zinc Tetra(4-pyridyl)porphyrin Single Crystalline Cubes
title_sort	reverse anti-solvent crystallization process for the facile synthesis of zinc tetra(4-pyridyl)porphyrin single crystalline cubes
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/79d4664dbe5e46ad9b5bef7158b6c73d
work_keys_str_mv	AT yohwanpark reverseantisolventcrystallizationprocessforthefacilesynthesisofzinctetra4pyridylporphyrinsinglecrystallinecubes AT misunhong reverseantisolventcrystallizationprocessforthefacilesynthesisofzinctetra4pyridylporphyrinsinglecrystallinecubes AT jinyoungkoo reverseantisolventcrystallizationprocessforthefacilesynthesisofzinctetra4pyridylporphyrinsinglecrystallinecubes AT minkyunglee reverseantisolventcrystallizationprocessforthefacilesynthesisofzinctetra4pyridylporphyrinsinglecrystallinecubes AT jinholee reverseantisolventcrystallizationprocessforthefacilesynthesisofzinctetra4pyridylporphyrinsinglecrystallinecubes AT daejunmoon reverseantisolventcrystallizationprocessforthefacilesynthesisofzinctetra4pyridylporphyrinsinglecrystallinecubes AT sohyeongsohn reverseantisolventcrystallizationprocessforthefacilesynthesisofzinctetra4pyridylporphyrinsinglecrystallinecubes AT taihajoo reverseantisolventcrystallizationprocessforthefacilesynthesisofzinctetra4pyridylporphyrinsinglecrystallinecubes AT wootaiklim reverseantisolventcrystallizationprocessforthefacilesynthesisofzinctetra4pyridylporphyrinsinglecrystallinecubes AT hyunseoblim reverseantisolventcrystallizationprocessforthefacilesynthesisofzinctetra4pyridylporphyrinsinglecrystallinecubes AT heecheulchoi reverseantisolventcrystallizationprocessforthefacilesynthesisofzinctetra4pyridylporphyrinsinglecrystallinecubes
_version_	1718388964393484288

Reverse Anti-solvent Crystallization Process for the Facile Synthesis of Zinc Tetra(4-pyridyl)porphyrin Single Crystalline Cubes

Ejemplares similares