Torpor enhances synaptic strength and restores memory performance in a mouse model of Alzheimer’s disease

Torpor enhances synaptic strength and restores memory performance in a mouse model of Alzheimer’s disease

Abstract Hibernation induces neurodegeneration-like changes in the brain, which are completely reversed upon arousal. Hibernation-induced plasticity may therefore be of great relevance for the treatment of neurodegenerative diseases, but remains largely unexplored. Here we show that a single torpor...

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Autores principales: Christina F. de Veij Mestdagh, Jaap A. Timmerman, Frank Koopmans, Iryna Paliukhovich, Suzanne S. M. Miedema, Maaike Goris, Rolinka J. van der Loo, Guido Krenning, Ka Wan Li, Huibert D. Mansvelder, August B. Smit, Robert H. Henning, Ronald E. van Kesteren
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/79d911a2ec34496183b119acd53c6f51
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