Upregulated Guanine Deaminase Is Involved in Hyperpigmentation of Seborrheic Keratosis via Uric Acid Release

Seborrheic keratosis, which is a benign tumor composed of epidermal keratinocytes, develops common in the elderly. Uric acid generated by upregulated guanine deaminase (<i>GDA</i>) has been identified to cause UV-induced keratinocyte senescence in seborrheic keratosis. Seborrheic keratos...

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Bibliographic Details
Main Authors: Kyung Ah Cheong, In Sup Kil, Hyuk Wan Ko, Ai-Young Lee
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/79ddfd26e3474fd5bffd9533f7ba9a9e
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