Comprehensive study of nuclear receptor DNA binding provides a revised framework for understanding receptor specificity
The type II nuclear receptors (NRs) and the retinoid X receptor (RXR) form heterodimeric transcription factors to regulate development, metabolism, and inflammation. Here the authors employ protein-binding microarrays to comprehensively analyze the DNA binding of 12 NR:RXRα heterodimers, and report...
Guardado en:
Autores principales: | Ashley Penvose, Jessica L. Keenan, David Bray, Vijendra Ramlall, Trevor Siggers |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/79e323cec1f2436e87f4111b7b42c180 |
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