Posterior association networks and functional modules inferred from rich phenotypes of gene perturbations.

Combinatorial gene perturbations provide rich information for a systematic exploration of genetic interactions. Despite successful applications to bacteria and yeast, the scalability of this approach remains a major challenge for higher organisms such as humans. Here, we report a novel experimental...

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Bibliographic Details
Main Authors: Xin Wang, Mauro A Castro, Klaas W Mulder, Florian Markowetz
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Online Access:https://doaj.org/article/79ee6acd63d44cc3a060fcbb94e8580b
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