Posterior association networks and functional modules inferred from rich phenotypes of gene perturbations.
Combinatorial gene perturbations provide rich information for a systematic exploration of genetic interactions. Despite successful applications to bacteria and yeast, the scalability of this approach remains a major challenge for higher organisms such as humans. Here, we report a novel experimental...
Guardado en:
Autores principales: | Xin Wang, Mauro A Castro, Klaas W Mulder, Florian Markowetz |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
|
Materias: | |
Acceso en línea: | https://doaj.org/article/79ee6acd63d44cc3a060fcbb94e8580b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Perturbation-based gene regulatory network inference to unravel oncogenic mechanisms
por: Daniel Morgan, et al.
Publicado: (2020) -
Perturbation biology: inferring signaling networks in cellular systems.
por: Evan J Molinelli, et al.
Publicado: (2013) -
Inferring multilayer interactome networks shaping phenotypic plasticity and evolution
por: Dengcheng Yang, et al.
Publicado: (2021) -
Tissue-specific functional networks for prioritizing phenotype and disease genes.
por: Yuanfang Guan, et al.
Publicado: (2012) -
Inferring the gene network underlying the branching of tomato inflorescence.
por: Laura Astola, et al.
Publicado: (2014)