Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation
An extensive RNA binding protein atlas (RBPome) for primary T cells would be a useful resource. Here the authors use two different methods to characterise the mouse and human T cell RBPome and show regulation of Roquin-1/2 dependent and independent pathways.
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Nature Portfolio
2021
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oai:doaj.org-article:79f61fbb2db9463391f56fc5ab732e2e2021-12-02T16:38:26ZDefining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation10.1038/s41467-021-25345-52041-1723https://doaj.org/article/79f61fbb2db9463391f56fc5ab732e2e2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25345-5https://doaj.org/toc/2041-1723An extensive RNA binding protein atlas (RBPome) for primary T cells would be a useful resource. Here the authors use two different methods to characterise the mouse and human T cell RBPome and show regulation of Roquin-1/2 dependent and independent pathways.Kai P. HoefigAlexander ReimChristian GallusElaine H. WongGesine BehrensChristine ConradMeng XuLisa KifingerTaku Ito-KurehaKyra A. Y. DefournyArie GeerlofJosef MautnerStefanie M. HauckDirk BaumjohannRegina FeederleMatthias MannMichael WiererElke GlasmacherVigo HeissmeyerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Kai P. Hoefig Alexander Reim Christian Gallus Elaine H. Wong Gesine Behrens Christine Conrad Meng Xu Lisa Kifinger Taku Ito-Kureha Kyra A. Y. Defourny Arie Geerlof Josef Mautner Stefanie M. Hauck Dirk Baumjohann Regina Feederle Matthias Mann Michael Wierer Elke Glasmacher Vigo Heissmeyer Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation |
| description |
An extensive RNA binding protein atlas (RBPome) for primary T cells would be a useful resource. Here the authors use two different methods to characterise the mouse and human T cell RBPome and show regulation of Roquin-1/2 dependent and independent pathways. |
| format |
article |
| author |
Kai P. Hoefig Alexander Reim Christian Gallus Elaine H. Wong Gesine Behrens Christine Conrad Meng Xu Lisa Kifinger Taku Ito-Kureha Kyra A. Y. Defourny Arie Geerlof Josef Mautner Stefanie M. Hauck Dirk Baumjohann Regina Feederle Matthias Mann Michael Wierer Elke Glasmacher Vigo Heissmeyer |
| author_facet |
Kai P. Hoefig Alexander Reim Christian Gallus Elaine H. Wong Gesine Behrens Christine Conrad Meng Xu Lisa Kifinger Taku Ito-Kureha Kyra A. Y. Defourny Arie Geerlof Josef Mautner Stefanie M. Hauck Dirk Baumjohann Regina Feederle Matthias Mann Michael Wierer Elke Glasmacher Vigo Heissmeyer |
| author_sort |
Kai P. Hoefig |
| title |
Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation |
| title_short |
Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation |
| title_full |
Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation |
| title_fullStr |
Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation |
| title_full_unstemmed |
Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation |
| title_sort |
defining the rbpome of primary t helper cells to elucidate higher-order roquin-mediated mrna regulation |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/79f61fbb2db9463391f56fc5ab732e2e |
| work_keys_str_mv |
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