The core-promoter factor TRF2 mediates a Fruitless action to masculinize neurobehavioral traits in Drosophila

fruitless (fru) is an important sex-determinant gene that controls the expression of neuroanatomical sex differences in Drosophila. Here the authors report that a core-promoter factor, TRF2, suppresses a male-type neurite specification through direct interaction with FruBM isoform at the robo1 targe...

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Autores principales:	Zahid Sadek Chowdhury, Kosei Sato, Daisuke Yamamoto
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/79f6e07656c84a5899a4df6440d7fe9f
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spelling	oai:doaj.org-article:79f6e07656c84a5899a4df6440d7fe9f2021-12-02T17:06:10ZThe core-promoter factor TRF2 mediates a Fruitless action to masculinize neurobehavioral traits in Drosophila10.1038/s41467-017-01623-z2041-1723https://doaj.org/article/79f6e07656c84a5899a4df6440d7fe9f2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01623-zhttps://doaj.org/toc/2041-1723fruitless (fru) is an important sex-determinant gene that controls the expression of neuroanatomical sex differences in Drosophila. Here the authors report that a core-promoter factor, TRF2, suppresses a male-type neurite specification through direct interaction with FruBM isoform at the robo1 target gene promoter.Zahid Sadek ChowdhuryKosei SatoDaisuke YamamotoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zahid Sadek Chowdhury Kosei Sato Daisuke Yamamoto The core-promoter factor TRF2 mediates a Fruitless action to masculinize neurobehavioral traits in Drosophila
description	fruitless (fru) is an important sex-determinant gene that controls the expression of neuroanatomical sex differences in Drosophila. Here the authors report that a core-promoter factor, TRF2, suppresses a male-type neurite specification through direct interaction with FruBM isoform at the robo1 target gene promoter.
format	article
author	Zahid Sadek Chowdhury Kosei Sato Daisuke Yamamoto
author_facet	Zahid Sadek Chowdhury Kosei Sato Daisuke Yamamoto
author_sort	Zahid Sadek Chowdhury
title	The core-promoter factor TRF2 mediates a Fruitless action to masculinize neurobehavioral traits in Drosophila
title_short	The core-promoter factor TRF2 mediates a Fruitless action to masculinize neurobehavioral traits in Drosophila
title_full	The core-promoter factor TRF2 mediates a Fruitless action to masculinize neurobehavioral traits in Drosophila
title_fullStr	The core-promoter factor TRF2 mediates a Fruitless action to masculinize neurobehavioral traits in Drosophila
title_full_unstemmed	The core-promoter factor TRF2 mediates a Fruitless action to masculinize neurobehavioral traits in Drosophila
title_sort	core-promoter factor trf2 mediates a fruitless action to masculinize neurobehavioral traits in drosophila
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/79f6e07656c84a5899a4df6440d7fe9f
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The core-promoter factor TRF2 mediates a Fruitless action to masculinize neurobehavioral traits in Drosophila

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