SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography

Here the authors visualize SARS-CoV-2 infected cells by in situ cryo-electron tomography, delineating the structural organization and conformational changes that occur during virus replication and budding; and provide insight into vRNP architecture and RNA networks in double membrane vesicles.

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Autores principales:	Steffen Klein, Mirko Cortese, Sophie L. Winter, Moritz Wachsmuth-Melm, Christopher J. Neufeldt, Berati Cerikan, Megan L. Stanifer, Steeve Boulant, Ralf Bartenschlager, Petr Chlanda
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7a032aa67d8d4439ad792070dcdf9862
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spelling	oai:doaj.org-article:7a032aa67d8d4439ad792070dcdf98622021-12-02T17:06:32ZSARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography10.1038/s41467-020-19619-72041-1723https://doaj.org/article/7a032aa67d8d4439ad792070dcdf98622020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19619-7https://doaj.org/toc/2041-1723Here the authors visualize SARS-CoV-2 infected cells by in situ cryo-electron tomography, delineating the structural organization and conformational changes that occur during virus replication and budding; and provide insight into vRNP architecture and RNA networks in double membrane vesicles.Steffen KleinMirko CorteseSophie L. WinterMoritz Wachsmuth-MelmChristopher J. NeufeldtBerati CerikanMegan L. StaniferSteeve BoulantRalf BartenschlagerPetr ChlandaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Steffen Klein Mirko Cortese Sophie L. Winter Moritz Wachsmuth-Melm Christopher J. Neufeldt Berati Cerikan Megan L. Stanifer Steeve Boulant Ralf Bartenschlager Petr Chlanda SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography
description	Here the authors visualize SARS-CoV-2 infected cells by in situ cryo-electron tomography, delineating the structural organization and conformational changes that occur during virus replication and budding; and provide insight into vRNP architecture and RNA networks in double membrane vesicles.
format	article
author	Steffen Klein Mirko Cortese Sophie L. Winter Moritz Wachsmuth-Melm Christopher J. Neufeldt Berati Cerikan Megan L. Stanifer Steeve Boulant Ralf Bartenschlager Petr Chlanda
author_facet	Steffen Klein Mirko Cortese Sophie L. Winter Moritz Wachsmuth-Melm Christopher J. Neufeldt Berati Cerikan Megan L. Stanifer Steeve Boulant Ralf Bartenschlager Petr Chlanda
author_sort	Steffen Klein
title	SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography
title_short	SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography
title_full	SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography
title_fullStr	SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography
title_full_unstemmed	SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography
title_sort	sars-cov-2 structure and replication characterized by in situ cryo-electron tomography
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/7a032aa67d8d4439ad792070dcdf9862
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SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography

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