Characterization of Schu S4 aro mutants as live attenuated tularemia vaccine candidates

There is a need for development of an effective vaccine against Francisella tularensis, as this potential bioweapon has a high mortality rate and low infectious dose when delivered via the aerosol route. Moreover, this Tier 1 agent has a history of weaponization. We engineered targeted mutations in...

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Autores principales: Aimee L. Cunningham, Barbara J. Mann, Aiping Qin, Araceli E. Santiago, Christen Grassel, Michael Lipsky, Stefanie N. Vogel, Eileen M. Barry
Formato: article
Lenguaje:EN
Publicado: Taylor & Francis Group 2020
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Acceso en línea:https://doaj.org/article/7a18e541a1a649a5a930e352b3947dc8
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