Characterization of Schu S4 aro mutants as live attenuated tularemia vaccine candidates
There is a need for development of an effective vaccine against Francisella tularensis, as this potential bioweapon has a high mortality rate and low infectious dose when delivered via the aerosol route. Moreover, this Tier 1 agent has a history of weaponization. We engineered targeted mutations in...
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Auteurs principaux: | Aimee L. Cunningham, Barbara J. Mann, Aiping Qin, Araceli E. Santiago, Christen Grassel, Michael Lipsky, Stefanie N. Vogel, Eileen M. Barry |
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Format: | article |
Langue: | EN |
Publié: |
Taylor & Francis Group
2020
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Accès en ligne: | https://doaj.org/article/7a18e541a1a649a5a930e352b3947dc8 |
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