A least angle regression model for the prediction of canonical and non-canonical miRNA-mRNA interactions.

microRNAs (miRNAs) are short non-coding RNAs with regulatory functions in various biological processes including cell differentiation, development and oncogenic transformation. They can bind to mRNA transcripts of protein-coding genes and repress their translation or lead to mRNA degradation. Conver...

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Autores principales: Julia C Engelmann, Rainer Spang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/7a2441c68f164d59b96693bfaee39c19
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