ResA3: a web tool for resampling analysis of arbitrary annotations.

Resampling algorithms provide an empirical, non-parametric approach to determine the statistical significance of annotations in different experimental settings. ResA(3) (Resampling Analysis of Arbitrary Annotations, short: ResA) is a novel tool to facilitate the analysis of enrichment and regulation...

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Autores principales:	Aaron Ruhs, Franz Cemic, Thomas Braun, Marcus Krüger
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/7a28d00133a941e997d0da6d8a64f244
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spelling	oai:doaj.org-article:7a28d00133a941e997d0da6d8a64f2442021-11-18T07:59:49ZResA3: a web tool for resampling analysis of arbitrary annotations.1932-620310.1371/journal.pone.0053743https://doaj.org/article/7a28d00133a941e997d0da6d8a64f2442013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23382850/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Resampling algorithms provide an empirical, non-parametric approach to determine the statistical significance of annotations in different experimental settings. ResA(3) (Resampling Analysis of Arbitrary Annotations, short: ResA) is a novel tool to facilitate the analysis of enrichment and regulation of annotations deposited in various online resources such as KEGG, Gene Ontology and Pfam or any kind of classification. Results are presented in readily accessible navigable table views together with relevant information for statistical inference. The tool is able to analyze multiple types of annotations in a single run and includes a Gene Ontology annotation feature. We successfully tested ResA using a dataset obtained by measuring incorporation rates of stable isotopes into proteins in intact animals. ResA complements existing tools and will help to evaluate the increasing number of large-scale transcriptomics and proteomics datasets (resa.mpi-bn.mpg.de).Aaron RuhsFranz CemicThomas BraunMarcus KrügerPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 1, p e53743 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Aaron Ruhs Franz Cemic Thomas Braun Marcus Krüger ResA3: a web tool for resampling analysis of arbitrary annotations.
description	Resampling algorithms provide an empirical, non-parametric approach to determine the statistical significance of annotations in different experimental settings. ResA(3) (Resampling Analysis of Arbitrary Annotations, short: ResA) is a novel tool to facilitate the analysis of enrichment and regulation of annotations deposited in various online resources such as KEGG, Gene Ontology and Pfam or any kind of classification. Results are presented in readily accessible navigable table views together with relevant information for statistical inference. The tool is able to analyze multiple types of annotations in a single run and includes a Gene Ontology annotation feature. We successfully tested ResA using a dataset obtained by measuring incorporation rates of stable isotopes into proteins in intact animals. ResA complements existing tools and will help to evaluate the increasing number of large-scale transcriptomics and proteomics datasets (resa.mpi-bn.mpg.de).
format	article
author	Aaron Ruhs Franz Cemic Thomas Braun Marcus Krüger
author_facet	Aaron Ruhs Franz Cemic Thomas Braun Marcus Krüger
author_sort	Aaron Ruhs
title	ResA3: a web tool for resampling analysis of arbitrary annotations.
title_short	ResA3: a web tool for resampling analysis of arbitrary annotations.
title_full	ResA3: a web tool for resampling analysis of arbitrary annotations.
title_fullStr	ResA3: a web tool for resampling analysis of arbitrary annotations.
title_full_unstemmed	ResA3: a web tool for resampling analysis of arbitrary annotations.
title_sort	resa3: a web tool for resampling analysis of arbitrary annotations.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/7a28d00133a941e997d0da6d8a64f244
work_keys_str_mv	AT aaronruhs resa3awebtoolforresamplinganalysisofarbitraryannotations AT franzcemic resa3awebtoolforresamplinganalysisofarbitraryannotations AT thomasbraun resa3awebtoolforresamplinganalysisofarbitraryannotations AT marcuskruger resa3awebtoolforresamplinganalysisofarbitraryannotations
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ResA3: a web tool for resampling analysis of arbitrary annotations.

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