Genome-wide association study of medication-use and associated disease in the UK Biobank

An understanding of the genetic variants associated with medication use may shed light on the underlying biological pathways of disease, and aid in drug development. Here, Wu and colleagues conduct a GWAS for self-reported medication-use in the UK Biobank, finding more than 500 independent variants...

Full description

Saved in:
Bibliographic Details
Main Authors: Yeda Wu, Enda M. Byrne, Zhili Zheng, Kathryn E. Kemper, Loic Yengo, Andrew J. Mallett, Jian Yang, Peter M. Visscher, Naomi R. Wray
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Q
Online Access:https://doaj.org/article/7a2b184ba1cd45c1aa138f729b16fae8
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:An understanding of the genetic variants associated with medication use may shed light on the underlying biological pathways of disease, and aid in drug development. Here, Wu and colleagues conduct a GWAS for self-reported medication-use in the UK Biobank, finding more than 500 independent variants and many promising leads for future work.