The Gq signalling pathway inhibits brown and beige adipose tissue
Brown and beige adipose tissues contribute to organismal energy expenditure by generating heat. Here, Klepac et al. survey G protein-coupled receptors in brown fat and show that Gq-coupled receptors inhibit expression of thermogenic proteins in mice and in human adipocytes.
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Nature Portfolio
2016
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| Acceso en línea: | https://doaj.org/article/7a2bc9f5eaee4df68bf0b1b7a219eba3 |
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oai:doaj.org-article:7a2bc9f5eaee4df68bf0b1b7a219eba32021-12-02T16:49:58ZThe Gq signalling pathway inhibits brown and beige adipose tissue10.1038/ncomms108952041-1723https://doaj.org/article/7a2bc9f5eaee4df68bf0b1b7a219eba32016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms10895https://doaj.org/toc/2041-1723Brown and beige adipose tissues contribute to organismal energy expenditure by generating heat. Here, Klepac et al. survey G protein-coupled receptors in brown fat and show that Gq-coupled receptors inhibit expression of thermogenic proteins in mice and in human adipocytes.Katarina KlepacAna KilićThorsten GnadLoren M. BrownBeate HerrmannAndrea WildermanAileen BalkowAnja GlödeKatharina SimonMartin E. LidellMatthias J. BetzSven EnerbäckJürgen WessMarc FreichelMatthias BlüherGabi KönigEvi KostenisPaul A. InselAlexander PfeiferNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Katarina Klepac Ana Kilić Thorsten Gnad Loren M. Brown Beate Herrmann Andrea Wilderman Aileen Balkow Anja Glöde Katharina Simon Martin E. Lidell Matthias J. Betz Sven Enerbäck Jürgen Wess Marc Freichel Matthias Blüher Gabi König Evi Kostenis Paul A. Insel Alexander Pfeifer The Gq signalling pathway inhibits brown and beige adipose tissue |
| description |
Brown and beige adipose tissues contribute to organismal energy expenditure by generating heat. Here, Klepac et al. survey G protein-coupled receptors in brown fat and show that Gq-coupled receptors inhibit expression of thermogenic proteins in mice and in human adipocytes. |
| format |
article |
| author |
Katarina Klepac Ana Kilić Thorsten Gnad Loren M. Brown Beate Herrmann Andrea Wilderman Aileen Balkow Anja Glöde Katharina Simon Martin E. Lidell Matthias J. Betz Sven Enerbäck Jürgen Wess Marc Freichel Matthias Blüher Gabi König Evi Kostenis Paul A. Insel Alexander Pfeifer |
| author_facet |
Katarina Klepac Ana Kilić Thorsten Gnad Loren M. Brown Beate Herrmann Andrea Wilderman Aileen Balkow Anja Glöde Katharina Simon Martin E. Lidell Matthias J. Betz Sven Enerbäck Jürgen Wess Marc Freichel Matthias Blüher Gabi König Evi Kostenis Paul A. Insel Alexander Pfeifer |
| author_sort |
Katarina Klepac |
| title |
The Gq signalling pathway inhibits brown and beige adipose tissue |
| title_short |
The Gq signalling pathway inhibits brown and beige adipose tissue |
| title_full |
The Gq signalling pathway inhibits brown and beige adipose tissue |
| title_fullStr |
The Gq signalling pathway inhibits brown and beige adipose tissue |
| title_full_unstemmed |
The Gq signalling pathway inhibits brown and beige adipose tissue |
| title_sort |
gq signalling pathway inhibits brown and beige adipose tissue |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/7a2bc9f5eaee4df68bf0b1b7a219eba3 |
| work_keys_str_mv |
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1718383165571072000 |