Energy efficiency trade-offs drive nucleotide usage in transcribed regions

Substantial cellular resources are devoted to nucleotide biosynthesis. Here the authors propose that transcribed regions prefer ‘cheaper’ nucleotides, which appears true for synonymous sites, although more expensive nucleotides coding for cheaper amino acids are selected for at non-synonymous sites....

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Autores principales: Wei-Hua Chen, Guanting Lu, Peer Bork, Songnian Hu, Martin J. Lercher
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/7a32783021324680993871e53a96b6e5
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spelling oai:doaj.org-article:7a32783021324680993871e53a96b6e52021-12-02T14:38:33ZEnergy efficiency trade-offs drive nucleotide usage in transcribed regions10.1038/ncomms113342041-1723https://doaj.org/article/7a32783021324680993871e53a96b6e52016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11334https://doaj.org/toc/2041-1723Substantial cellular resources are devoted to nucleotide biosynthesis. Here the authors propose that transcribed regions prefer ‘cheaper’ nucleotides, which appears true for synonymous sites, although more expensive nucleotides coding for cheaper amino acids are selected for at non-synonymous sites.Wei-Hua ChenGuanting LuPeer BorkSongnian HuMartin J. LercherNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Wei-Hua Chen
Guanting Lu
Peer Bork
Songnian Hu
Martin J. Lercher
Energy efficiency trade-offs drive nucleotide usage in transcribed regions
description Substantial cellular resources are devoted to nucleotide biosynthesis. Here the authors propose that transcribed regions prefer ‘cheaper’ nucleotides, which appears true for synonymous sites, although more expensive nucleotides coding for cheaper amino acids are selected for at non-synonymous sites.
format article
author Wei-Hua Chen
Guanting Lu
Peer Bork
Songnian Hu
Martin J. Lercher
author_facet Wei-Hua Chen
Guanting Lu
Peer Bork
Songnian Hu
Martin J. Lercher
author_sort Wei-Hua Chen
title Energy efficiency trade-offs drive nucleotide usage in transcribed regions
title_short Energy efficiency trade-offs drive nucleotide usage in transcribed regions
title_full Energy efficiency trade-offs drive nucleotide usage in transcribed regions
title_fullStr Energy efficiency trade-offs drive nucleotide usage in transcribed regions
title_full_unstemmed Energy efficiency trade-offs drive nucleotide usage in transcribed regions
title_sort energy efficiency trade-offs drive nucleotide usage in transcribed regions
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/7a32783021324680993871e53a96b6e5
work_keys_str_mv AT weihuachen energyefficiencytradeoffsdrivenucleotideusageintranscribedregions
AT guantinglu energyefficiencytradeoffsdrivenucleotideusageintranscribedregions
AT peerbork energyefficiencytradeoffsdrivenucleotideusageintranscribedregions
AT songnianhu energyefficiencytradeoffsdrivenucleotideusageintranscribedregions
AT martinjlercher energyefficiencytradeoffsdrivenucleotideusageintranscribedregions
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