Energy efficiency trade-offs drive nucleotide usage in transcribed regions

Substantial cellular resources are devoted to nucleotide biosynthesis. Here the authors propose that transcribed regions prefer ‘cheaper’ nucleotides, which appears true for synonymous sites, although more expensive nucleotides coding for cheaper amino acids are selected for at non-synonymous sites....

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Main Authors:	Wei-Hua Chen, Guanting Lu, Peer Bork, Songnian Hu, Martin J. Lercher
Format:	article
Language:	EN
Published:	Nature Portfolio 2016
Subjects:	Science Q
Online Access:	https://doaj.org/article/7a32783021324680993871e53a96b6e5
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spelling	oai:doaj.org-article:7a32783021324680993871e53a96b6e52021-12-02T14:38:33ZEnergy efficiency trade-offs drive nucleotide usage in transcribed regions10.1038/ncomms113342041-1723https://doaj.org/article/7a32783021324680993871e53a96b6e52016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11334https://doaj.org/toc/2041-1723Substantial cellular resources are devoted to nucleotide biosynthesis. Here the authors propose that transcribed regions prefer ‘cheaper’ nucleotides, which appears true for synonymous sites, although more expensive nucleotides coding for cheaper amino acids are selected for at non-synonymous sites.Wei-Hua ChenGuanting LuPeer BorkSongnian HuMartin J. LercherNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wei-Hua Chen Guanting Lu Peer Bork Songnian Hu Martin J. Lercher Energy efficiency trade-offs drive nucleotide usage in transcribed regions
description	Substantial cellular resources are devoted to nucleotide biosynthesis. Here the authors propose that transcribed regions prefer ‘cheaper’ nucleotides, which appears true for synonymous sites, although more expensive nucleotides coding for cheaper amino acids are selected for at non-synonymous sites.
format	article
author	Wei-Hua Chen Guanting Lu Peer Bork Songnian Hu Martin J. Lercher
author_facet	Wei-Hua Chen Guanting Lu Peer Bork Songnian Hu Martin J. Lercher
author_sort	Wei-Hua Chen
title	Energy efficiency trade-offs drive nucleotide usage in transcribed regions
title_short	Energy efficiency trade-offs drive nucleotide usage in transcribed regions
title_full	Energy efficiency trade-offs drive nucleotide usage in transcribed regions
title_fullStr	Energy efficiency trade-offs drive nucleotide usage in transcribed regions
title_full_unstemmed	Energy efficiency trade-offs drive nucleotide usage in transcribed regions
title_sort	energy efficiency trade-offs drive nucleotide usage in transcribed regions
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/7a32783021324680993871e53a96b6e5
work_keys_str_mv	AT weihuachen energyefficiencytradeoffsdrivenucleotideusageintranscribedregions AT guantinglu energyefficiencytradeoffsdrivenucleotideusageintranscribedregions AT peerbork energyefficiencytradeoffsdrivenucleotideusageintranscribedregions AT songnianhu energyefficiencytradeoffsdrivenucleotideusageintranscribedregions AT martinjlercher energyefficiencytradeoffsdrivenucleotideusageintranscribedregions
_version_	1718390959411036160

Energy efficiency trade-offs drive nucleotide usage in transcribed regions

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