Energy efficiency trade-offs drive nucleotide usage in transcribed regions
Substantial cellular resources are devoted to nucleotide biosynthesis. Here the authors propose that transcribed regions prefer ‘cheaper’ nucleotides, which appears true for synonymous sites, although more expensive nucleotides coding for cheaper amino acids are selected for at non-synonymous sites....
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Main Authors: | Wei-Hua Chen, Guanting Lu, Peer Bork, Songnian Hu, Martin J. Lercher |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2016
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Online Access: | https://doaj.org/article/7a32783021324680993871e53a96b6e5 |
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