Energy efficiency trade-offs drive nucleotide usage in transcribed regions

Substantial cellular resources are devoted to nucleotide biosynthesis. Here the authors propose that transcribed regions prefer ‘cheaper’ nucleotides, which appears true for synonymous sites, although more expensive nucleotides coding for cheaper amino acids are selected for at non-synonymous sites....

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Bibliographic Details
Main Authors: Wei-Hua Chen, Guanting Lu, Peer Bork, Songnian Hu, Martin J. Lercher
Format: article
Language:EN
Published: Nature Portfolio 2016
Subjects:
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Online Access:https://doaj.org/article/7a32783021324680993871e53a96b6e5
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