A synergetic effect of BARD1 mutations on tumorigenesis

A synergetic effect of BARD1 mutations on tumorigenesis

Mutations in the BARD1 gene have been identified as risk factors in breast and ovarian cancers. Here the authors reveal a synergetic effect between the occurance of two cis mutations in the BARD1 gene affecting the cellular DNA damage response and consequently tumorigenesis.

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Detalles Bibliográficos
Autores principales: Wenjing Li, Xiaoyang Gu, Chunhong Liu, Yanyan Shi, Pan Wang, Na Zhang, Rui Wu, Liang Leng, Bingteng Xie, Chen Song, Mo Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
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Acceso en línea:https://doaj.org/article/7a37045af7a44a0f82d41c601a782661
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