Microclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear
Blood clotting is a complex process involving platelet adhesion and clot stiffening. Here the authors present a microfluidic system to recapitulate the dynamic changes in clot mechanics under physiological shear.
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Nature Portfolio
2019
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oai:doaj.org-article:7a3a33d9afd740029c0735340ec2278f2021-12-02T17:32:24ZMicroclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear10.1038/s41467-019-10067-62041-1723https://doaj.org/article/7a3a33d9afd740029c0735340ec2278f2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10067-6https://doaj.org/toc/2041-1723Blood clotting is a complex process involving platelet adhesion and clot stiffening. Here the authors present a microfluidic system to recapitulate the dynamic changes in clot mechanics under physiological shear.Zhaowei ChenJiankai LuChangjie ZhangIsaac HsiaXinheng YuLeo MareckiEric MareckiMohammadnabi AsmaniShilpa JainSriram NeelameghamRuogang ZhaoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
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Science Q Zhaowei Chen Jiankai Lu Changjie Zhang Isaac Hsia Xinheng Yu Leo Marecki Eric Marecki Mohammadnabi Asmani Shilpa Jain Sriram Neelamegham Ruogang Zhao Microclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear |
description |
Blood clotting is a complex process involving platelet adhesion and clot stiffening. Here the authors present a microfluidic system to recapitulate the dynamic changes in clot mechanics under physiological shear. |
format |
article |
author |
Zhaowei Chen Jiankai Lu Changjie Zhang Isaac Hsia Xinheng Yu Leo Marecki Eric Marecki Mohammadnabi Asmani Shilpa Jain Sriram Neelamegham Ruogang Zhao |
author_facet |
Zhaowei Chen Jiankai Lu Changjie Zhang Isaac Hsia Xinheng Yu Leo Marecki Eric Marecki Mohammadnabi Asmani Shilpa Jain Sriram Neelamegham Ruogang Zhao |
author_sort |
Zhaowei Chen |
title |
Microclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear |
title_short |
Microclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear |
title_full |
Microclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear |
title_fullStr |
Microclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear |
title_full_unstemmed |
Microclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear |
title_sort |
microclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/7a3a33d9afd740029c0735340ec2278f |
work_keys_str_mv |
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