Microclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear

Blood clotting is a complex process involving platelet adhesion and clot stiffening. Here the authors present a microfluidic system to recapitulate the dynamic changes in clot mechanics under physiological shear.

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Autores principales: Zhaowei Chen, Jiankai Lu, Changjie Zhang, Isaac Hsia, Xinheng Yu, Leo Marecki, Eric Marecki, Mohammadnabi Asmani, Shilpa Jain, Sriram Neelamegham, Ruogang Zhao
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/7a3a33d9afd740029c0735340ec2278f
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spelling oai:doaj.org-article:7a3a33d9afd740029c0735340ec2278f2021-12-02T17:32:24ZMicroclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear10.1038/s41467-019-10067-62041-1723https://doaj.org/article/7a3a33d9afd740029c0735340ec2278f2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10067-6https://doaj.org/toc/2041-1723Blood clotting is a complex process involving platelet adhesion and clot stiffening. Here the authors present a microfluidic system to recapitulate the dynamic changes in clot mechanics under physiological shear.Zhaowei ChenJiankai LuChangjie ZhangIsaac HsiaXinheng YuLeo MareckiEric MareckiMohammadnabi AsmaniShilpa JainSriram NeelameghamRuogang ZhaoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Zhaowei Chen
Jiankai Lu
Changjie Zhang
Isaac Hsia
Xinheng Yu
Leo Marecki
Eric Marecki
Mohammadnabi Asmani
Shilpa Jain
Sriram Neelamegham
Ruogang Zhao
Microclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear
description Blood clotting is a complex process involving platelet adhesion and clot stiffening. Here the authors present a microfluidic system to recapitulate the dynamic changes in clot mechanics under physiological shear.
format article
author Zhaowei Chen
Jiankai Lu
Changjie Zhang
Isaac Hsia
Xinheng Yu
Leo Marecki
Eric Marecki
Mohammadnabi Asmani
Shilpa Jain
Sriram Neelamegham
Ruogang Zhao
author_facet Zhaowei Chen
Jiankai Lu
Changjie Zhang
Isaac Hsia
Xinheng Yu
Leo Marecki
Eric Marecki
Mohammadnabi Asmani
Shilpa Jain
Sriram Neelamegham
Ruogang Zhao
author_sort Zhaowei Chen
title Microclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear
title_short Microclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear
title_full Microclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear
title_fullStr Microclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear
title_full_unstemmed Microclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear
title_sort microclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/7a3a33d9afd740029c0735340ec2278f
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