Apigenin-induced lysosomal degradation of β-catenin in Wnt/β-catenin signaling

Apigenin-induced lysosomal degradation of β-catenin in Wnt/β-catenin signaling

Abstract The bioflavonoid apigenin has been shown to possess cancer-preventive and anti-cancer activities. In a drug screening, we found that apigenin can inhibit Wnt/β-catenin signaling, a pathway that participates in pivotal biological functions, which dis-regulation results in various human disea...

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Autores principales: Chung-Ming Lin, Hsin-Han Chen, Chun-An Lin, Hui-Chung Wu, Jim Jinn-Chyuan Sheu, Hui-Jye Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/7a3f49179f4840959ec4a17293cc46c9
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