A molecular vision of fungal cell wall organization by functional genomics and solid-state NMR

The fungal cell wall is a complex structure composed mainly of glucans, chitin and glycoproteins. Here, the authors use solid-state NMR spectroscopy to assess the cell wall architecture of Aspergillus fumigatus, comparing wild-type cells and mutants lacking major structural polysaccharides, with ins...

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Autores principales: Arnab Chakraborty, Liyanage D. Fernando, Wenxia Fang, Malitha C. Dickwella Widanage, Pingzhen Wei, Cheng Jin, Thierry Fontaine, Jean-Paul Latgé, Tuo Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7a4748863df342f5a632b6cd415fa253
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Sumario:The fungal cell wall is a complex structure composed mainly of glucans, chitin and glycoproteins. Here, the authors use solid-state NMR spectroscopy to assess the cell wall architecture of Aspergillus fumigatus, comparing wild-type cells and mutants lacking major structural polysaccharides, with insights into the distinct functions of these components.